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I have been on Omeprazole 20mg twice a day for at least 5 years and have some concern about the known serious side effects eg bone thinning, kidney problems etc. I appreciate this is in a small number of patients but has anybody had problems with taking PPI's for a prolonged period and if so have you been able to switch to a viable alternative with less side effects. It appears as soon as you are diagnosed with Barratt's you are prescribed PPI's for the rest of your life.
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