Lumbosacrel Plexopathy

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Almost 3 years ago I got up out of a chair and experienced horrific pain in my knee, groin and back within 30 seconds I was paralysed in the left leg. I spent 1 week in hospital with a diagnoses of GBSyndrome. I was wrongly diagnosed and after many more tests a Neurologist diagnosed Lumbosacrel Plexopathy. My left knee is permanently numb, which has really hindered my day to day activities. Fortunately I am no longer paralysed in my leg, but the numbness is extremely uncomfortable as it is constantly there. I have had many months of Hydro and Physio but to no avail. My question is will the nerves in my left knee ever rejuvenate, or will this be as good as it gets. I have never had Chemo nor Have I got Diabetes. I do not know how and why this rare Peripheral Nerve disease has happened.

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3 Replies

  • Posted

    Have you ever been tested for a B12 or Folate deficiency?

    I know you say you don't have diabetes but the article below does suggest a connection between LP and B12. Unfortunately, a severe deficiency may cause damage to brain and nerve cells that is very difficult to reverse and early detection can be critical in preventing permanent neurological damage.

    https://patient.info/doctor/diabetic-amyotrophy-pro

    You will need to read down to the very bottom of the article.

    I am not a medically trained person but I've had Pernicious Anaemia (a form of B12 deficiency) for more than 46 years and I also have Type 2 Diabetes so for my permanently numb thighs it's a double whammy.

    I wish you well. 

    • Posted

      No never been tested for this. I will definitely look into this. Thank you for answering me. No one knows too much about this rare disease
    • Posted

      Symptoms of B12 deficiency tend to develop slowly and may not be recognised immediately. As the condition worsens, common symptoms include:

      Weakness and fatigue

      Light-headedness and dizziness

      Palpitations and rapid heartbeat

      Shortness of breath

      A sore tongue that has a red, beefy appearance

      Nausea or poor appetite

      Weight loss

      Diarrhoea

      Yellowish tinge to the skin and eyes

      If low levels of B12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms:

      Numbness and tingling in the hands and feet

      Difficulty walking

      Muscle weakness

      Irritability

      Memory loss

      Dementia

      Depression

      Psychosis

      Anyone at any age, can become B12 deficient. However, certain people are at an elevated risk. They include the following:

      Vegetarians, vegans and people eating macrobiotic diets.

      People aged sixty and over

      People who’ve undergone any gastric and/or intestinal surgery, including bariatric surgery for weight loss purposes (Gastric bypass).

      People who regularly use proton-pump- inhibitors. H2 blockers, antacids, Metformin, and related diabetes drugs, or other medications, or infections such as h-pylori that can interfere with B12 absorption.

      People who undergo surgeries or dental procedures involving nitrous oxide, or who use the drug recreationally.

      People with a history of eating disorders (anorexia or bulimia).

      People with a history of alcoholism.

      People with a family history of pernicious anaemia.

      People diagnosed with anaemia (including iron deficiency anaemia, sickle cell anaemia and thalassaemia).

      People with Crohn’s disease, irritable bowel syndrome, gluten enteropathy (celiac disease), or any other disease that cause malabsorption of nutrients.

      People with autoimmune disorders (especially thyroid disorders such as Hashimoto’s thyroiditis and Grave’s disease) Type 1 diabetes, vitiligo, lupus, Addison’s disease, ulcerative colitis, infertility, acquired agammaglobulinemia, or a family history of these disorders.

      Women with a history of infertility or multiple miscarriages.Can you "see yourself" among any of the above people?

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