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Hi everyone! I've been diagnosed through confirmed biopsies with both mast cell activation disease and granuloma annulare. I believe they are connected because my GA first appeared when my MCAD symptoms really ramped up.
I did some research and found Dr. Afrin (mast cell disease specialist) talking about GA being a symptom that doctors see but don't connect to MCAD because they don't know about MCAD. I also found a strong link between the TNF (tumor necrosis factor) mediator that my mast cells release and the formation of the granuloma rings.
Here's more proof: when I went on my mast cell stablizing medications my granuloma ring disappeared. If I get triggered badly or miss doses of medicine it comes back, as a fully formed ring. Otherwise it is gone, or looks gone at least.
So I thought I'd share this in case it is new information here and ask if anyone else has both of these rare diseases?
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