Methotrexate
Posted , 9 users are following.
Hello all, I joined this group for my husband who has PMR. He was diagnosed about 14 months ago. Predinisone and other meds have not been successful to treat him so he was put on Methotrexate this week. Does anyone else here have experience with this med, good or bad? Thanks
0 likes, 40 replies
Daniel1143 rose11340
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Rose, I am also a 62 year old male. Your husband's story touches me deeply. Praying for his improved health.
rose11340 Daniel1143
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Elijo rose11340
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How long did you court before you were married? I was widowed twice had been married to wonderful men, whom I had known well before marraige. Two years ago after 8 yrs. alone, i remarried after knowing him for only 8 months. Not really long enough, but we are working on it. Somestimes it can be very stressful. I'm sorry you have to go through all of that, it isn't easy for you.
rose11340 Elijo
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EileenH rose11340
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"The PMR seems to aggravate all the other conditions."
Or a vasculitis is aggravating all the others - and that might fit with the relatively sudden decline. I think you need to try to find a vasculitis specialist - are you in the UK?
Elijo rose11340
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When we are dating and attracted to the gentleman, we seem to fail to see some of the so called negative attributes, not that we all don't have them! If you really love or care deeply about him it's worth working on it. Fortunately my husband is in super health. He came from a different country where the "women follow the men" So we're working on it. Life is a challenge in so many ways, it does help us to grow. My first husband had COPD and severe ashmatic bronchitis and was very ill the last 2 yrs of his life, but very active before. I understand whatit is like and wish you the best. Elinor.
rose11340 Elijo
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FlipDover_Aust rose11340
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Hi Rose
I have PMR and was put on MTX just over a year ago in an effort to bring my pred dose down which I wasn't able to budge from 20mg! It works as a steriod 'sparer' and I was able to get down quite significantly over a few months to a more reasonable 10mg.
My rhuemy has said on a few occassions *his* goal is to get me off pred, and I've recently (4 months ago) started on Actemra, a biologic usually prescribed for RA. It's further assisted me to reduce my pred dose and I'm currently on 4.5mg. of course *my* goal is to get to as low a dose as possible that controls the symptoms of PMR!
I have a couple of questions though - if pred isn't working, then are you sure the diagnosis correct? If it's PMR then MTX won't help by itself. It just 'helps the pred work better'.
What other meds has he tried, given pred is the only drug known to work effectively on PMR symptoms?
Has he been told to wean off pred yet? What happens if (when) the sypmtoms return with a vengance?
FlipDover_Aust
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Grandpa_Pete rose11340
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I'm not going to comment on many of the isuues being discussed here! Suffice it to say I am an exception. I was put on methotrexate for my PMR because I refused to take preds. It took several weeks but it worked for me. I have been pain free for about a year now and returned to all my activities including league table tennis. I'm hoping soon to taper from my current dosage. And I have questioned my original PMR diagnosis - my specialist is still insisting it was correct.
Daniel1143 Grandpa_Pete
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Might want to challenge that diagnosis. Methotrexate is often used to combat rheumatoid arthritis or a related inflammatory disease. When MT works, it is often a sign of something other than PMR. That and the fact that you were able to live for weeks without prednisone, the only true "go to" for PMR leads me to suspect whether you should be convinced of your doctor's conviction. As we have seen, they are often wrong,
rose11340 Daniel1143
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ptolemy rose11340
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Rose I am so sorry for all the stress you are going through. I am amazed that someone with PMR can go to the gym every day, I find I need a day to recover! I suppose it depends what he does when he is there of course. I think the advice you have been given is good, don't get stressed, if someone does not want to do something they will not listen to others giving advice. I do hope things get sorted out.
rose11340 ptolemy
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EileenH rose11340
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FlipDover_Aust EileenH
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Exactly my thoughts - at least 10-12 weeks. And it's not like you wake up and feel better.....more like a gradual improvement and the ability to reduce the pred, leading you to feel better.