Methotrexate and alcohol

Posted , 104 users are following.

Hi there,

I've only yesterday started on my methotrexate tablets and have just started reading the online forums and have became very worried! The number of people who are losing their hair seems incredible, is this a common side effect?

I'm 23 years old and drinking and work in a bar while i'm studying at University. Drinking and going out is a massive part of my life and I was just wondering if anyone could tell me if it's still possible to carry this on at all? I usually go out roughly twice a week and can drink up to 3 nights. I know of course I will be cutting down massively, but can I still do it at all?

I can only find negative forums on here about the drug and it's making me feel like the side effects aren't worth the risk... Does anyone feel like they can still live their lifes on this drug and it is worth taking?

Thanks for any advice you can give! A bit worried here...

7 likes, 107 replies

107 Replies

Prev Next
  • Posted

    Hello, I have been on MTX for a couple years, 2.5mg, 6 a week, has anyone noticed when you drink you joints hurt and painful, was wondering cuz I have noticed I guess you would call it a flare?
    • Posted

      Hey,

      Click here to view image

      Has anyone else noticed this?

      Thanks

    • Posted

      The lumps may either be OA Hebredian lumps or RA nodules. Ask your Rhuemy ?
    • Posted

      I have only been on MTX since April 2014. 2.5 x 8 a week, on Fridays. I felt releived to read your post. My daughter got married last Saturday and I had completely forgot about being careful with alcohol. I didn't think I drank that much but was feeling quite squiffy after a few glasses of wine and the toast. The next day I was in so much pain I thought I had been hit by a bus. I could barely get out of bed. My knee joints, feet and wrists were incredibly painful. We are now three days on and although not as painful my joints are still uncomfortable. Its like having an extended hangover. I certainly will be wary about drinking in future.
    • Posted

      I've always noticed that drinking causes me increase pain even before taking MTX, it must just cause more inflammation.  If I have even one drink I have pain, I don't drink much anymore as a result between that and the hangovers it's not worth it. My Rheumy doesn't allow for more than 2 drinks /month. I went to Costa Rica  this winter for my anniversary, needless to say I drank too much. My labs were all out if wack, and I eat well and exercise. To all you college kids my advice is cut down major on the alcohol intake, that's was a major source of misery for me in that decade of my life. Don't destroy your liver and especially your kidneys. 

    • Posted

      Yes I too do not stick to the rule with drinking. I also get small lumps that appear on my fingers. I have been on methotrexate for about 4 months. I go in next week for my 3 month blood tests. This will be my 2nd round. Last check my blood tests all came back normal. It will be very interesting to see my results considering just going through a crazy, busy, lots of parties holiday season. I definetly do not take a drink on my medication day. And take it easy on the day after. 
  • Posted

    hiya! I have found this discussion so helpful! Just wondering if anyone can offer me some advice please.

    Im 26, have psoriatic arthrits and ive been taking methotrexate (6 tabs of 2.5 mg) weekly for about a year and a half with no real side effects and no problems in my blood tests.  I get my bloods tested every month but am going travelling around Australia for at least a year in a couple of months and will probably find it hard to ensure I get to a GP every month for my blood tests.  Does anyone know if this will be a massive issue?  Have spoke to GP here in UK and obviously they say i should try get it tested every month.

    Click here to view image

    • Posted

      I've always been told that blood tests are important but would think there's some way of still getting yours checked especially in a country like Australia who have a similar health system to ours. Every 3 mths is usually enough. Go on the NRAS freephone helpline and ask them OR contact your local NHS travel clinic. They have all the health advice for anywhere in the world. You'll also need to make sure your travel insurance covers you for pre existing conditions ! Have a brilliant time.
    • Posted

      Thanks Connie, didn't even know there was a NRAS helpline! Will call on Monday. And ye health insurance is all covered.

      Thanks!

    • Posted

      Think about it...If you've had no real problems for a year i wouldn't worry about the blood tests every month. Trust your body and how you feel. If you skip a few months and have some fun  great! If you have a test after mising a few months and your tests aren't normal than go back to them every month! ( Levels being off for a few months is not a big deal. Enjoy your travel and LIVE!!)
  • Posted

    Hello!

    So, I should note that I've only been on methotrexate for about six months so far. I was also afraid of losing my hair and being nauseous and sick a lot, because these are problems my grandmother--who suffered from RA as I do--had. She had really thick hair that became incredibly thin and fragile while on methotrexate, though she never actually lost it to the point of appearing balding.

    When I expressed these concerns to my doctor she told me that a lot of new information has come to light about treating RA since my grandmother suffered with it, and that many of the negative side effects were actually a result of vitamin deficiencies caused by the meds that can be circumvented by taking supplements. The side effects and their severity can also differ based on dose; I'm on a relatively low dose because that is all that's required to deal with my symptoms.

    Right now, she has me on methotrexate and plaquenil, as well as a daily dose of calcium, vitamin D, B12, and folic acid supplements. And I am happy to say that so far, I feel pretty great. I have not noticed any problems with my hair. In fact, it's just as thick and unmanageable as ever! :D The only notable side effect I've seen with methotrexate is that on the day I take it, I'm usually very, very tired. Also, I notice that I used to be able to pull multiple all-nighters in a row, and I can't really do that anymore. Not in the sense that I get sick or anything, moreso in the sense that I just crash completely...I will fall asleep and not wake up until my body decides I've had enough rest!

    I split the dose of six pills once a week into two pills three times, spaced four hours apart over the course of a day, and that has helped a lot. I've also found that getting an hour or two of extra sleep the night before seems to keep me from being tired. If all else fails, a cup of coffee fixes me right up!

    As for alcohol, there are a couple of reasons you don't want to be drinking. First of all, the methotrexate already gives your liver some extra work, so adding alcohol to that significantly increases your risk of liver disease or damage. Especially if you're drinking multiple times a week. The other reason is that methotrexate can cause drowsiness and nausea, so adding alcohol (which can also cause both) to that mix is just a recipe for disaster.

    My workplace is very centered around social drinking, but I've found that I can still have fun with my coworkers while sipping on a diet Coke or a ginger ale, even if at first it made me feel a bit square. My doctor's recommendation was that I could indulge in a glass of wine on my birthday, but no more than that.

    It sucks sometimes, being 25 and unable to partake with the rest of my peer group, but honestly? I'd rather give up drinking than go back to the unbearable pain in my hands and feet from the RA, and the constant feeling of exhaustion and frustration from always being in that much pain.

    • Posted

      Hi there, having to deal with this at such a young age is the pits & I really feel for you. You're right though that your health & wellness are more important than a drink. I'm older than you so in a way that's even harder as I've had longer to be used to a different lifestyle. That said, I feel exactly like you and keep my alcohol consumption very low. I'm on 20 gm of Mtx as a weekly injection - much better than when I took it in a tablet form. I also have 1 x 50 gm Enbrel injection weekly. I take folic acid every day but the Mtx day and a Calcium/Vit D3 twice a day. Mayer ask about your Mtx as an injection 
    • Posted

      GOOD FOR YOU! Your health is more important than a drink. I had a huge lump on my wrist surgically removed and it grew back within a month. (It turned out to be RA nodule) I was a HUGE drinker. I take Piroxicam as well as theMethotrexate for the Swelling that goes with my RA.) The pills we are all taking are not kind on your stomach so I recommend Omeprazol for the day you take your pills and the day after. (It's over the counter) I also recommed a Pneumonia and Shingle Vaccine as your immune system wears down a bit and it's easier to get sick and stay sick longer. Drinking doesn't help your immune system and makes your liver process liquor slower. (The reason for alcohol tolerance being lower and the increase in hangovers) If some one reads this and is also taking medication for depression/Anxiety etc. it's a lot on your liver but in most cases still cool, but throw somw booze into the equation and you are playing with fire! It could take a long while to catch up to you IF it does but why chance it. Smoke an occasional Joint or excercise if you need to relax or chill. 
    • Posted

      The reason you're told to take your methotrexate once per week is because it gives your stomach and liver etc time to recover between each dose. This method has been found to cause the least damage so you shouldn't split your dose like you have been. I just joined so I could tell you. I have RA and my boyfriend is a GP. 

      I have have never really reduced my alcohol intake since starting Mtx and Humira. I forget to be honest as taking Mtx doesn't cause me any problems besides hair loss. My bloods are all normal so hopefully I don't have massive liver damage! 

      I'm interested reading the comments about supplements to reduce hair loss because all I was advised to take is folic acid, which I do. My hair still falls out more than normal - it's not thin but I always have millions of baby hairs sprouting out and it's not nice like it used to be. 

      I've been on Mtx for 6 years starting when I was 25. I was really ill for a while - at one point before diagnosis I woke up in the morning and just couldn't move. I'm so grateful for these drugs as now I'm basically 100% just perhaps more easily tired than other people. I do worry about the long term side effects though as it's harsh stuff. 

      I feel eel for all of you young 'uns (I'm 31 now) but know that RA and similar diseases don't have to mean massively altering your lifestyle. Look after yourselves and read as much info as possible to be informed in your own healthcare. Doctors are not always that great! Make sure you have a good specialist who you trust. I go to one in Oxford even though I now live in Gloucestershire as I believe their care is superior. Ask me any questions you have I am happy to help. 

    • Posted

      Hi, 

      I am currently 18 years old and diagnosed with Crohn's disease in June 2014. I have been taking Humira and Methotrexate since the first week in Oct, Methotrexate weekly on friday and Humira biweekly on friday. I take Folic acid tablets every day except for my MTX injection days. I will be starting college soon I am wondering when it is acceptable to drink alcohol on these medications, and if I do, how much. 

      Thank you!

    • Posted

      Hi

      i am so pleased I have joined this site. I was diagnosed with RA in September. My rheumatologist wanted me to take methotrexate straight away but after reading the possible scary side affects and the fact I could not have a social drink again I refused. He put me on sulfasazeline which unfortunately has not worked. So regrettably I am now taking methotrexate after reading some of these posts it's nice to know that I can still have a drink if I choose to. The rheumy told me not to drink at all which I'm sorry but  it's to much to take in is it just me being selfish but to me you only have one life make the most of it. I am 53 by the way and love going out socialising especially after a hard slog at work all week. If it shows in my blood then maybe I will cut down but up to now I've been ok it's just the guilt I feel afterwards 

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.