Methotrexate + Antibiotics
Posted , 4 users are following.
I am taking 4 x 2.5 mg methotrexate tablets every thursday followed by 2 folic acid tablets on Saturday. I am at present run down with a cold, cough, aches and upset stomach. Can I take antibiotics with the above?
0 likes, 3 replies
1_hand_works cockerpoo
Posted
You have to be really careful which antibiotics you take as there are certain ones which you definitely shouldn't have (these include some penicillins). Your GP can check but there should be some prescription notes with your MTX which tell you which ones you have to avoid. I got a severe infection and needed the antibiotics, so I had to leave off the MTX until I finished my antibiotics. To be quite honest I was that unwell, my joint pains and rash were the last things I was worried about as the infection markers in my blood tests were sky high. If you definitely have an infection and need antibiotics your clinicians may just stop the MTX until you are better. Best to get some blood tests done first to see which antibiotics you need, to make sure you weigh up the pros and cons. Good luck and hope you feel better soon
patricia73863 cockerpoo
Posted
Lisa_Batts cockerpoo
Posted
I've been told by my doctor that whatever antibiotics I am on stop the MTX. It makes a lot of sense because the MTX is an immune suppressant so whilst taking it your body can't fight the infection. I actually stop MTX if I have a bad illness even when not on antibiotics (viral) as it gives the body more fight against the disease.
This of course is just how I've learned to do it.
One thing I know for sure is Trimethoprim (antibiotic) with MTX can be fatal ... I know because my previous doctor prescribed it and I ended up in hospital for ten days. This is not actually yet in the 'guide book' they use for interactions although my pharmacist is getting it put in there
Regards
Lisa