Methotrexate Injection Reaction

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Hi there all.

I'm looking for some advice please. I did my injection a week ago into my leg. I've never had an issue before ( Injection since November and previously I was on tablets) yesterday, the injection site started to really itch and has become quite sore andpainful. I don't know if to do this week's injection or not. Any thoughts? Thanks in advance.

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4 Replies

  • Posted

    If I were you I'd get in touch with either your Dr or a pharmacist for advice. It may be that it's become infected

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  • Posted

    Occasinally get itching in MTX injections site, try not to scratch as that only makes it worse, and I watch it carefully usually settles for me within 36 hours or so.

    You may have an infection in needle site, probabaly celulitis at this stage.

    Is it red and angry and hot as well as itchy you need to see a Dr.

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  • Posted

    I have some itching and redness for a day or so after. I have never gotten an infection but I have put a little ice on it to calm it down a little


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  • Posted

        A week seems like a long time before the soreness started after your MTX injection

    I used to give myself humira injection and the site would become very red, itchy, hard lump by the 3rd day and stay that way for another few days

      Told the doctor who suggested I use ice at the injection site and I could apply a bit of cortisone cream  on it.   That did help.  But I would check with your doctor to be sure it's ok to take the next injection and for advice.

       Hope it has eased up by now though. 

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