Methotrexate Injections

Posted , 8 users are following.

Hi,

I've been on methotrexate injections now for about two years. Prior to this I was on the tablets and had to change to the injections because they made me feel very sick. After the two years on these injections I'm also starting to feel sick for quite a long period after I inject. I'm not sure if it's just a feeling I associate with taking methotrexate after having had problems with the tablets or if this is also making me feel sick? I was under the impression that because the injections bypass your digestive system the sick feeling shouldn't happen but I don't really understand the way the methotrexate works.

If anyone has experience the same as this I would be very interested in hearing from you to hear about your experiences.

Thanks for reading and hope to hear from someone.

Joseph

1 like, 10 replies

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10 Replies

  • Posted

    Hi,

    I felt sick on the tablets which I had taken over a couple of years and my doctor suggested I inject instead. I believe the med was also altering my mood as I became very edgy and angered easily so I wanted to give it up completely. So I went more plant-based and refused the injection idea. What I found was the more I went with a diverse Whole-Foods Plant-based diet the better I felt. I was vegetarian at the time and then switched overnight to vegan.

    The first change that told me I was onto something was 40 days in at 100% vegan. No meat/dairy/processed food/preservatives/sugars/oils. I continued the diet and the next significant change happened somewhere between 80-90 days. What I felt at each change was less pain and more energy.

    Its been over 7 months since I started this journey and today marks 28 days of 0 pain. I have been fully off of all medications including Methotrexate (which I had at 25mg per week at the time). I also was taking vicoden and ibuprofen and haven't touched either of those as well.

    At this point I've turned my health around in a big way. btw: I went fully raw vegan 100% about 22ish days ago. What I highly recommend is 70% or above raw foods during your day. I also recommend getting rid of gluten and breads (if you read about breads you will find they do nothing for the body). What you want to do is give yourself nothing but the best and simplest foods that nature offers.

    Look up turmeric and black pepper as a pain reliever. I used it for two weeks straight and then tapered it as the pain lessened during workouts. I haven't used it at all in the past month or so but I know its there if I need. Look up Apple Cider Vinegar and what that can do for your health. This was also a pain reliever and generally a great way to increase my health. Both of the above taste horrible so you swig them. Don't drink the ACV straight though you have to do it with a lot of water. ACV causes potassium loss so counter it with lots of fruits with potassium. Turmeric and black pepper can be swigged with just a little water. Limes are acid but alkaline to the body. Great pain relief too so have 1 a day. There is lots of research to do but it will change your life and you won't have to rely on doctors.

    So there are a couple of tips on top of the WFPB. Now, research everything you can about the plant-based diet. Get involved with the vegan and whole foods plant based communities so you can learn to get the right balance of nutrients. You don't want to do something wrong and then feel fatigued. When you do, figure it out. I had bumps along the way but I learned and got on track.

    I'd be happy to offer more advice but the key is really just getting started. Look up every youtube and research paper out there to begin understanding what's behind your health. PCRM org has a 21 day vegan starter free class that's good but again, my advice is simple (I eat 10-15 bananas a day, a couple of avocados (for the oil), a huge variety of greens, and a wide variety of fruits, and nuts. For drinks its water, almond milk, flax milk, hemp milk,. I've pretty much given up grains but will eat rice or quinoa on occasion. I love beer but I pretty much have to give that up too as I find I feel better without it. I believe its the sugar from beer which is the problem but don't quote me on that as I haven't done research on everything, I just know what works.

    You might question why doctors don't give you advice like this. The reason they don't is they weren't taught nutrition. Look up the facts on what it takes to become a doctor and you'll find that they have a very basic understanding. Just ask your doctor what percentage black pepper increases absorption of nutrients in the body. The answer is up to 2000% but most doctors don't know this. Black pepper is medicine.

    I hope this helps someone and it would be great to hear if someone else can replicate. I know that Mimi Kirk said she went raw vegan to get rid of her arthritis and high cholesterol. btw: I can physically run again this year where I couldn't even walk last year. I look better and people around me notice. So now that I've helped myself I wanted to help others for free by telling a bit of my story.

    Feel free to ask me any questions.

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  • Posted

    Hi Joseph,

    I feel exactly the same as you. I began taking methotrexate in pill form 4 years ago which caused nausea for approx 2 days afterwards. I switched to injections a 3 years ago to try and reduce the nausea but it is still the same. I tried injecting late a night to avoid a few hours of sickness, but in my case I feel my worst 24 hours after the injection. The nausea remains for the next 24 hours and is usually gone when I wake on day 3.

    I take Folic acid and have tried other anti nausea drugs which didn't help. Everything else I have tried to reduce the nausea (ginger, chewing gum etc) just became associated with nausea, until the very sight of them made me feel sick. I have also started feeling sick just before I inject as I know what is coming! I think dehydration makes the nausea worse, so it might help a bit if you drink plenty of water on the first day.

    No one knows how MTX works but as it's chemo it will do bad as well as good things. Unfortunately I think we are stuck with this until they develop a wonder drug to replace MTX which could take some time sad

    Just keep reminding yourself what the joint pain was like before the MTX. I think that was much worse than 2 days of nausea.

    Good Luck

    Nick

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    • Posted

      I was looking on here today to see how others deal with the nausea. I do agree with you Nick. A little nausea is nothing compared to the way I felt before I took Methotrexate. The pain was SO MUCH worse, I could barely function. Thanks for reminding me of that.
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  • Posted

    Hi nick,

    Thanks very much for replying. It interesting to hear from someone who has also had problems with the injections (since it seems the majority of people are ok on them). I am also taking a biological drug called embrel which is luckily very good. I've recently completely stopped my methotrexate due to the side effects and am only on embrel now which seems to be fine for me (at least up to now). All seems good up to now and not too much stiffness!!

    I would be interested in knowing how you get on with your drugs and hope you start to feel better on it.

    Once again thanks for the reply and have a nice christmas.

    Joe

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  • Posted

    Read Colin T. Campbell's Rethinking The Science of Nutrition. You don't need a "wonder drug", you need proper nutrition. For instance, it's well known that refined sugars are bad for bones. It's also known that meat is an inflammatory and dairy is horrible for lots of reasons. When you know this and drop them from your diet you start the repair process. That is, if you start also focusing on eating right. Please read what I wrote and ask me questions. Diet is key to a healthy life and most of us were taught wrong. I went from not walking and being placed on mtx to changing my diet and getting rid of all meds. At this point I haven't taken any medication In over 9 months. Even caught a bad cold and didn't take a single drop of any med for it. I'm not against medications when needed but I think most people that suffer from arthritis, and and even other conditions, don't realize that there's a solution in a proper diet. It takes many months to repair the body but it can be done. You may not be "perfect" but you probably won't need meds or can reduce them dramatically. The only time that I find myself having a problem with arthritis is when I cheat on my diet such as drinking alcohol or not eating enough raw foods. I'm not the only one to discover this. Mimi Kirk discussed why she went raw vegan. Look her up.

    Don't first look to the big pharmaceutical companies to save you, look to what your planet has already provided for you.

    Best of luck resolving your health issues,

    John

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  • Posted

    Don't focus on the "cure", focus on the "cause" and you will find the cure.
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  • Posted

    I was on the pill form of methotrexate a few years ago, stop due to planned pregnancy and now started the injections in nov...i really want to be off this drug, so I changed my diet no breads, or dairy, paleo style diet....when does a person try stopping the drug?
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  • Posted

    Hi

    I am in the same position at the moment done the tablets for approximately1+ years but then nausea then am now on injections but again feeling sick thought it might be due to the build up of doing it and then the fact I don't like putting it in my body so have only been taking it every two weeks - I feel terrible today and so bad that I have come on here looking for maybe and answer? I am worried about changing to something else whilst my symptoms are reasonably controlled - have so much to do looking after two boys work etc cant afford to keep feeling like this either?? At 36 years old I still have many years with this condition and want to be as fit and healthy as I can be Any advice greatly appreciated

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  • Posted

    Hi

    I too had problems with the tablet form of methotrexate. I have now been injecting since last year and was ok until they added sulphasalizine tablets in January. I couldn't tolerate them so stopped. Now I feel sick every day and im seriously thinking about stopping them altogether.

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  • Posted

    folic acid, ondansetron, metoclopramide
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