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I've discontinued taking Sulphasalazine as it was making me increasingly nauseous and with each increase in dose the pain increased exponentially. The rheumatologist has started me on Hydroxychloroquine and upped my Methotrexate to once weekly injections. At the same time he also advised me that he doubts this regimine will help much due to the severity of the RA; however, I will need to continue with them for another three months to qualify for biologicals which provide a wider choice of drugs, or as I prefer to call them 'toxins'.
A question for those on injected methotrexate: does a higher dose rate of methotrexate when injected have the same side effects as orals or are side effects more or less severe?
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