Mirtazapine 15mg to 30mg....do u feel like crap every time dose is increased???

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Recently got diagnosed with adjustment disorder due to being diagnosed with wegners last year, with GAD and major depressive disorder as a secondary diagnosis. Symtoms initially we're lack of appetite, stomach in knots in the, no energy, did not feel like moving from the couch, and just crying. Went to the hospital several times because never felt this way before. After going to the hospital a few times and getting all kinds of tests done with no bad results asked to speak to a psychiatrist. Was put on 7.5 mg mirtazapine and felt myself within a week...than about 2 to 3 weeks later one day just woke up not feeling like me...lost my appetite again, began feeling like doing nothing just sitting on the couch ..no energy. They uped my dose to 15mg... appetite slowly came back after a week and only really felt like me in the evenings and night. Mornings slowly started to improve but still rough...waking up feeling just not like myself....blah with a nervous feeling in my stomach. So they uped my dose to 30mg after going on the 15mg for 2 weeks. Took the 30 last night and again mornings became rough..just not feeling not right....is it normal to regress when uping the dose???? I think that every time I feel off I just start panicking that that awful feeling us coming back or wegners is showing it's ugly head again.....I've never suffered from anxiety or depression before so this is all new. I just don't understand how completely normal I felt on the 7.5 mg of mirtazapine than one day snap I just regressed.

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  • Posted

    I’m so sorry to hear all your  issues with the changing of your strengths of mirtazapine 

    I’ve only been on one strength 7.5 for 8 months and I am hoping to stop taking it all together 

    I’ve never increased or decreased the strength so I’m unable to answer your question......sorry!

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  • Posted

    I’ve been on mirtazapine for almost 3 years. I started at 15mg for many of the same reasons as you... GAD, major depressive disorder, panic disorder, lack of appetite, no energy, exaggerated emotional response... I also suffer from insomnia so they put me on mertazipine for the added benefits of drowsiness and appetite stimulation. They tried to increase me to 30 and it made me feel awful. Also gave me terrible lower back pains. To be honest I don’t feel like it’s been all that beneficial. Caused more side effects than it’s helped. But I tried most everything else all with awful side effects. This was the most mild in terms of bad reaction. My advice, give it a good couple of months before you decide whether or not to stay on it or come off. Also, you know your body better than anyone. If you feel the dose increase is unnecessary or that you were better off on the lower dose, tell your prescribing doctor. They’ll treat you like a lab rat if you allow them. 
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  • Posted

    I’m going through the same issue 1 week and abit ago my dose got increased from 15mg to 30mg and feeling the anxiety full force worse than before! Just hope it lifts!  ( I have only been on this med 5 weeks) I think when we change the dose it takes another 2-4 weeks for the benefit to kick in again ( I read somewhere it’s just like starting mirtazapine all over again) so it like a reset!! Hope we both feel better soon! 
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    • Posted

      Hi, just wondering how you feeling with the increase? I always tend to feel like me in the late afternoons early evenings. This is my 5th day on the 45 mg...hoping your right and something magical happens soon. So far not great.

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