Mirtazapine long lasting side effect on one dose of 7.5

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i tried mirt back in August slept well but boy did I regret it the next day and the day after and the next, trouble is I wasn't sleeping well. But had some sort of motivation. And never felt depressed, maybe low because of worry and anxiety that I constantly had.

so I don't get the whole lethargy, if something can knock you out like this for longer than all the anaesthetics I can remember how can it be good for you?

 I've been in decline ever since, and 2 days ago, I thought that was it. Can't carry on working and went crazy to a point I couldn't control. But for some reason I managed to calm down by talking to people. Everybody drums in my head I can't help you you need ad. And I am scared of them. I've taken traz for  2 week and didn't get on with em either.

so 2 days ago I ring my psychiatrist in panic and he only rings me back at 8pm. I'm on the phone with him. And tells me you need sleep. I usually sleep 4hrs a day in bits.

he says take mirt now so I do. I'm going through the same symptoms again. The tingly ness in my jaw as if the anaesthetics of a dentist is wearing off. That lasted 2 weeks by the way. And the fatigue for around well. Still have it today.

just wanted to share my experience. I know people will say not everyone gets that bad on them but I did, and I think it's one of those either great drugs or really bad drugs depending on you. But how can anyone carry on thinking this will get better and push yourself to keep taking them. It's absurd to me?

im really upset that I've been as stupid as to take it again.

ruins my life which was already crap.

my moms friend takes it and she's much better. How bizarre. Why can't I find a treatment like that? 

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12 Replies

  • Posted

    Dear ol

    I am sorry you are having such trouble. I well understand it and will add my own horror story with low dose Mirt.

    I was prescribed 15mg to improve sleep. One dose was much too strong. Next evening bit my pill into 1/4s. That worked quite well and after a week increase to 1/3rd  5mg sounds sensible. GP agreed with my chages. After three weeks I had a new supply from a different maker. Still taking 5mg and I was in a deep depression. After a week got pills from the original maker and climbed out of the depression - took about a month. 

    what would have happened if I had started with the wrong manufacturer?

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  • Posted

    How very odd but I've heard that before, generic and all that. Can you tell me what ones are good and which are bad? Any different markings?

     

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    • Posted

      It’s unfortunate, but all generics are not equal. Once a patent runs out, generic manufactures can obtain the right to make a med. But one important factor is the patent of the binders of the med, what holds the active ingredient together, never expires. The binders determine how fast a med is released into the body. Generic manufactures have to develop their own set of binders, and as a result, the generic drug may release the med too fast or too slow. It varies from one generic manufacture to another. I have epilepsy and take 2 generic meds. As I have found out, the generic manufacture can make a difference. Most generics are now made in India or China. Quality control? My generic mirtazapine is made by Apotex, which seems to work for me. You can search the web on other people’s experience with different generic manufactures. I live in the U.S. and can’t request a specific generic manufacture even with a Dr’s note. My insurance only goes through one drug store chain. Insurance won’t cover the higher cost of non-generic meds. I have to accept what they give me. 
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    • Posted

      That is absolute madness. It's a drug. This is a very serious matter. So when they do studies. I wonder if it's on the generic or original drug?

      This is far too confusing

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    • Posted

      As I understand it, a generic manufacture are not required to have a single test study on their drug as long as it contains the active ingredient. The non-generic manufacture has to go through testing’s (maybe years) and studies before the Food and Drug Administration (FDA) in the U.S. will approve it. The non-generic manufacture has a patent on the drug for a number of years (I don’t know how many) before it can be made by generic manufactures. The FDA has received so many numerous complaints about some generic drugs, they began testing some of the generic meds which include seizure meds (which I take), heart meds, blood thinners and a few others at the top of the list last year. At least in the U.S., generic manufactures are granted a leeway of containing +/- 20% of the med., meaning it has a range of 80% to 120%. I think many Dr.’s aren’t aware of the differences between generics and non-generics. My specialist who prescribes my seizure meds and mirtazapine thinks there is no difference but he doesn’t take these meds himself. It was doing research on the web when I found out the binders, the glue, that holds and time releases the med into the system has a patent that never expires. If that patent on binders didn’t exist and generic manufactures could copy it, then I would agree there is no difference between non-generics and generics. I don’t know if drugs like mirtazapine are on the FDA list. I hope so. The FDA is a U.S. government agency, so I don’t expect the studies and results will be happening at lighting speed.

      I don’t know how to do it, but there needs to a petition put together on the web to pressure government agencies to test generics like mirtazapine.

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    • Posted

      This has suddenly made me think why Prozac didn't work 2nd time around. I only ever had one box which was called prozac the rest, Fluoxetine. Could this be really what's happening then the drug recipe differs?
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    • Posted

      so that may well be why mert from one manufacturer sent me into a deepdepression. Also my hormone therapy the three month release gave me problems and wore out at about two months but I do better on the one month (28 day or lunar month) lasts about 25 days. 
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  • Posted

    Getting back to your original questions....

    People carry on despite bad side effects because they know that they might be made better after a while.  The alternative is that they probably will not get better.     I do not call that absurd.   It takes courage.   

    These drugs are not a quick fix. Even 2 weeks is too short to know if a drug is right for you. 

     

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  • Posted

    It's 1 in morning fell asleep feeling OK. But now all woken up with at horrible body buzzing electric charge feeling. Same thing happened the following night after I first took it. This never happened before mirror. And its the feeling ever. Can't stop it. So up trying to breath but doesn't do a thing??? Horrible stuff
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    • Posted

      I wanted to chip in. Mirt evil stuff but seems to help people this is my experience

      7.5 was like a zombie

      15mg stomach issues

      Doc said up the Dose to 30 I said are you joking I am not going to take a higher dose it will mess me up more! He explained the side effects do not increase with dose. I tried it and he was right. Hope this helps

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