Mirtazapine tapering

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Hi everyone!

I have been on Mirtazapine for 16 weeks and have decided to come off it. This is for many reasons. The reason I was on it was due to some issues at work and I was getting quite anxious about things. However some of the side effects to this drug is just getting too much for me. I am on 30mg (only been at this dose for 2 weeks) and aim to try and taper down from it and come off them. 

Any thoughts, hints, help or tips would be fab x

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10 Replies

  • Posted

    May I ask why you are wanting to go off the medication I just started it 2 weeks ago only 15 mg  and it is not helping my anxiety at all 
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    • Posted

      A variety of reasons really. Although I do feel calmer with the anxiety side of things my anxiety was brought in by some work situations. Most of them are sorted now so I’m hoping I’ll be ok without them. 

      However I have suffered really badly with forms of gastric problems. I am lactose intolerant and can manage a lot of it without meds and haven’t had any bad flare ups in over 6 years. Since being in this I’ve had one problem after another with it and it’s got me to the degree now where I have been ill since Saturday and this is the only common factor over 5 days that I have. My stomachs massively swollen and tender and I can’t wear trousers. It’s making me unhappy with the side effects more than I was before I went on them so I’m biting the bullet to see how I get on without. 

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  • Posted

    There are lots of postings about tapering off Mirtazapine on this board.  You will need to take it slow on the taper otherwise you will incur bad side effects since you've been on the drug for 4 months.  In my experience, the drug had way too many side effects to make it even remotely beneficial.  I was on a very low dose (7.5 mg) too and still felt lousy.

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  • Posted

    With this medication it is best to go off them slowly I don’t know what it dose is but I was see your doctor Andre them to start to take you off them 
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  • Posted

    Hi Emma,  just wondering which way you've decided to taper off and how you are getting on? I just stopped taking 15mg after 13 weeks and it didn't go well for me! Back on them for a week but looking to taper off soon. My doctors seem to have no clue about withdrawal :-(

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    • Posted

      In all honesty Robbie, I’m just trying a reduction in it to see how it works. From reading through people’s experiences it is trial and error for each individual and from what I gather it takes a few weeks for any side effects to hit. At the minute I’m taking 30mg every other day. I think in a few weeks - months time I’ll look at reducing the dose and alternating when I take it. In all honesty I just want this out of my system but from what I’ve read I’m too scared to just stop them. I’m not sure if what I’m doing will work or if it’s right for me but I’m just going to have to take the leap and see. I hate this drug and hate how it makes me feel. 
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    • Posted

      I only have the dissolvable tablets as well so have to see how I can cut them down from the 30mg before the next stage. 
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    • Posted

      They also come in tablet form at 15mg which you can split in half. Could you request these or can't u take them?

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    • Posted

      As you start to get to the low doses on your taper, it will be more and more difficult to cut the dose using a pill cutter.  Ask your doctor about getting tablets that are the lowest dose, like 15 mg, not 30 mg.  This way each quarter tab is 3.75 mg.  You might also want to contact a compounding pharmacy to get a liquid formulation prepared from your pills.  This would be the preferred way to titer down as you can much more easily control the dosing using a syringe.

      Like Emma, I hate this drug.  I am glad to be off it.  I felt lousy pretty much 24-7.  Sometimes the cure really is worse than the disease. 

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    • Posted

      It’s only recently I’m seeing how awful this drug is. Today has been awful for me. With the weird limbo it puts you in. It scares me thinking that 3.75 it’s too high a dose to come off it. I think that speaks volumes for how horrible a drug it is. I can’t wait to get rid of it out of my system. I’d rather go back to how I was. 
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