Mirtazapine - weight gain!!!!
Posted , 67 users are following.
Hi,
I've never posted on a forum before but wondered if anyone could give me any advise.
I was diagnosed with depression just before christmas, I had quite a traumatic year with a series of bad events occurring, I was also getting married which I think was the only thing keeping me going, looking back now I realise I was slipping into a depressive state for about 2 months before I finally broke. I fell into quite a catatonic state being unable to function at even a basic level, it was as if my brain had just shut down.
The doc started me on sertraline but this made my anxiety so bad that I couldn't even go into my back garden, unable to leave the house or speak to anyone for a month, he then gave me citralopram, this reduced my anxiety but gave me insomnia, so I spent another month sleeping (or rather not sleeping) on my sofa and only getting a few hours of sleep here and there.
So my doc decided to try mirtazapine, my depression has reduced dramatically but I've have gained a lot of weight, which at first I thought was a welcome side effect compared to anxiety and insomnia but now this is really starting to lower my mood again,
When I was at the beginning of my illness and was unable to function, eating didn't even enter my head and I lost around a stone and a half (my usual weight sticks around 10 - 10 1/2 stone) to 9 stone, I looked really unwell at this weight, but since being on mirtazapine I have gained 2 1/2 stone in the first month (I'm into my second month now) and it's just staying there. I have tried changing my diet and exercising but I'm stuck at nearly 12 stone.
I look overweight, none of my clothes fit me and the worse part is that I look 6 months pregnant and because I am only just venturing out again after months of solitude, a lot of people think that I am pregnant and that's why they haven't seen me, I'm struggling to keep my smile and tell people I'm not as I am infertile and this has been one of the issues that led to my depression in the first place.
I'm not sure if anyone can help, I guess I'm just looking for advise on losing the weight or whether I should change my meds (again!!!!)
5 likes, 147 replies
KathyLBM bekstar
Posted
Hello, I am a 72-YO stage-4 cancer patient. I've been overweight for many years but after I was prescribed 15 mg Mirtazapine/day nearly a year ago I have gained at least 25 lb that I don't need. Otherwise I would say it's been a good antidepressant and has helped me deal with my condition. None of my doctors warned me about the weight gain, and even now they say it's all right. But I also have sciatica and cannot stand the extra weight. Also cannot exercise because of the sciatica and my weakened condition; anything I manage to do has a fierce payback the next day or even the rest of the week. I'm also on Gabapentin for the sciatica. Decided to taper off the Mirt gradually and try to do without it. I'm almost off it right now after 7 weeks of gradual reduction. I can notice I'm not as cheerful as before but I wouldn't say depressed. I have stopped gaining weight but haven't lost any. Seems like everything that's good for me in one way is bad for me in another.
NCNana KathyLBM
Posted
Kathy, I am so sorry for what you have been through. I too had breast cancer and am a 10 year survivor to date. I pray you will have a success story too. I turn 70 in just a week so we are close in age. In addition to the loss of two children, I have had numerous physical issues that have precluded me from doing a lot of exercise -- fibromyalgia, knee replacements, shoulder replacement a year ago, and some back surgery to help with nerve pain from stenosis, just two months ago. I have recovered from the surgery well, but the problems have not gone away so I am also still not able to be very active. I decided to go down on my dose of Mirtazapine from 15my to 7.5 to see if I can get off this med. I have done very well on the 7.5 for about 3 months now. When I return to the doctor soon, I will take more steps to try to get off these medications. I also take Wellbulerin 150mg so I don't know if the next step is to try to eliminate the Mirtazapine or reduse the Wellbuterin. At any rate, I am now up about 16 pounds from the lowest weight I got too after losing 85 pounds. This has been over the past 2 or so years. The bad truth is that once I gain a pound, I do not seem to be able to lose one! I know that it causes me to crave ice cream and I need to just stop eating it but easier said than done. I hope that you continue to do well off this medicine. You inspire me to go for it soon! God bless you!
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KathyLBM NCNana
Posted
Thank you, NCNana; I'm glad you're a 10-year cancer survivor! Mine is an unusual type, a leiomyosarcoma, that first showed up a little more than 4 years ago. I had surgery and they said they got it all, but it recurred 3 years later, last summer. I had radiation but not sure how much good it did. I have refused chemotherapy which my oncologist is pushing at me, having read that this type of cancer doesn't respond very well to either chemotherapy or radiation. I am resigned to my fate and just trying to get some projects important to me done before the inevitable. Dr. says I'm doing better than expected. But there is no cure for this cancer and it WILL take me out, maybe a few months, maybe a year or more. I'm not making long-term plans. But I have Jesus as my personal Savior and I know that when my eyes close here on earth they will open in heaven and his will be the first face I see.
As for the Mirtazapine, I wanted to get off it because of the weight gain and because it makes it so difficult to get up in the mornings (I've been taking it at night and it does help me sleep). This morning I got up in time to photograph the dawn for the first time in many months. I don't take a lot of prescriptions but there are two I don't dare get off of. Plus I take a lot of vitamins and minerals and one herbal preparation. I will just live as long as the Lord allows. 1 Cor. 10:13 says "There hath no temptation taken you but such as is common to man: but God is faithful, who will not suffer you to be tempted above that ye are able; but will with the temptation also make a way to escape, that ye may be able to bear it." I've claimed that verse. God bless you too, and may we meet in heaven!
NCNana KathyLBM
Posted
Oh, my dear sister in the Lord, Kathy, you are a breath of fresh air in the midst of such a potential storm. I am also a believer, for over 40 years now. And the two daughters I lost, Jennifer @ 40 in 2013, and then Diane at 41 in 2014 were also both believers. So I know the joy that awaits us all when we are reunited.
You have the most amazing outlook and I pray that should I face a reoccurrence of my cancer that I will face it with the same resolve that you have. I believe that I will!
I am part of a FB private group called Survivors Unlimited that is a group of women that either are dealing with cancer or have had it. I believe also that caregivers may join, but it is really focused on those of us who have faced the trials, treatments and testing of cancer. It has been a blessing to me and I have had the opportunity to be an encouragement to several of them. You would be a wonderful contributor to this website. We actually have to make a recommendation on each individual and then the creator of the FB page adds you. If you have FB, you would have to become my "friend", which I would love, then I would recommend you. No pressure if you keep your life private and FB private. Just a thought.
I want you to know that I know two women right now who have taken th same stand you have. One is now surviving 7 years and several years ago just gave the treatments up, and her life to God. I have to tell you she has done remarkable. She does continue to go in when she feels that she is digressing and in considerable more pain and they check her out and give her medications but she takes no more treatments.
I know another who has really reached out to a lot of new treatments, going to SK in NYC off and on. So in her journey and mission to "live with cancer", she is now on her 5th year. I actually befriended her through my daughter Diane when Diane met her and shared with her and started taking her to healing class at her church. She is still strong in her faith. The last few months she has posted about increasing pain and she is evaluated everything much as you are. You have to count whether the treatments will help or not, as they may not be a cure. God is in charge, He is the healer and one way or the other, based on His plan and timing, we will all be healed, whether it is for a longer time here on earth, or to go home to be with Him. As Paul said, and I just paraphrase, either way, we win! :-)
Thanks again for you information. The Mirtazapane also turned things around for me when I started. The Wellbutern I was taking just was not quite doing it. I had no other way to describe what I was experiencing other than just telling the doctor that I just had very melancholy momehts, sad momehts, still overcoming such a loss. And since I had lost 85 pounds and was continuing past what I would have been very satisfied with, she said "this will help with the weight loss...and will help with sleep too" Well, right she was..lol.. I should had said right away I don't want help with gaining weight! I had spent so many years very overweight and for the first time I was down to my wedding weight again but I took it. And the big thing about it was I immediately felt it working on my meoncholy moods.
I am so much more emotionally healthy now and that is why I want to try to wean off of it and see if I can do without it. They were labeling it as "situational depression" as I had never had a depressed day in my entire life! So my prayer is to eventually get off all of it.
I deal with fibromyalgia, having had it for over 30 years and also some joint and back issues so I am going to pain management for that. I also want to get off the pain medication and am trying some meds specific for fibromyalgia. I think the Lyrica I started is helping but I think it does also cause me to have a little disorientation for the first few hours of the morning but I'm not sure. We never know what causes what.
Didn't mean to go on so long but when you connect with another believer you automatically feel that connection.
God bless you and if you are interested in being a FB friend I am listed as Mariruth Redfern Pyatt. You can send me a friend request. Otherwise, I will stay in contact here.
Blessings!
KathyLBM NCNana
Posted
Hi Mariruth, I will look for you on FB and send you a friends request. I don't belong to many groups but I think yours might be of value to me, and me to them. I will answer at greater length later; got to rest now. I am Kathryn Meyer on FB.
nicola76452 bekstar
Posted
I have struggled with weight all my life, I’ve lost 11 1/2 stone. When my doctor prescribed Mirtazapine I was frightened as hell by the comments on here. I nearly stopped talking it. My experience has been, I’ve only consumed the calories I can burn in a day, I haven’t given into the hunger that Mirtazapine can cause, I’ve been going to the gym and I’m very pleased to say I’ve had no weight gain
Mirtazapine seems to be working for me, if you are sensible with what you eat, you should be fine. I asked my doctor and as far as she knows Mirtazapine does not slow your Metabolism down, it just increases hunger.
dawn47518 bekstar
Posted
I'm the same only recently went on mitrazepine but eating everything in sight I'm 13 stone so don't want to put on any more
NCNana dawn47518
Posted
Dawn, I'm just seeing this and wanted to offer some input from my experience. I too immediately started getting the urge for ice cream in particular. I was eating it about every night. l And on the nights I tried to not, I found myself doing so after midnight. But the most informative post I ever read about it was from someone who said that she knew she was in trouble when she found herself eating ice cream that was freezer burned at 3:00AM!!! This told the story for me. But the drug really helped me get past the melancholy I was feeling a lot of days even with taking the Wellbutrin. As I stated in another response, I weaned myself off it over about a 6 month period and have been fine without it. Good luck with resisting the ice cream! God bless!
kaz_52274 bekstar
Posted
KathyLBM kaz_52274
Posted
I had to get off it slowly, took several weeks. Since then I haven't gained any more weight, but haven't lost any either. I'm now on a different antidepressant, Bupropion (Wellbutin). It also works well for me but doesn't make me gain weight. Hope this helps.
kaz_52274 KathyLBM
Posted
KathyLBM kaz_52274
Posted
Yes, I was OK so long as I didn't go too fast. Had some strange dreams, which are listed as side effects going on and coming off, but nothing bad.
kaz_52274 KathyLBM
Posted
KathyLBM kaz_52274
Posted
kaz_52274 KathyLBM
Posted
Im so so sorry to hear this. 😢
NCNana KathyLBM
Posted
I stopped taking this med about 8 months ago. But I cannot take off the 20 pounds it put on me, about 10 each year. I have just had hip replacement surgery two days ago and that problem kept me still for the past 8 months. I pray that when I am fully recovered that I an return to an active life and maybe takes these extra pounds off. I will pray for you, Kathy.
NCNana kaz_52274
Posted
Best regards and prayers for good health to you!