Mirtazapine withdrawal, how long does it last?

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Hi, Just looking for some reassurance/support. I was on mirtazapine for about 6months. I went up to 45mg and decided to taper down as I felt they were making me worse and the weight gain was nasty. I felt fab tapering down and generally, its been better than I anticipated however, I'm approaching the 3rd week off of mirtazapine and have started to feel a bit anxious the last few days. I've read withdrawal peaks around the 3/4week mark, so I'm trying to stay positive that it will pass.

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  • Posted

    Does going Cold Turkey on Mirtazapine after taken it for 2 months Cause indigestion and nausea at night being off of it for about 3 weeks? Like  im feeling so sick nauseated that i have to sleep sitting up and burping and bloating all night. I am up most of the night walking back and fourth from the bathroom feeling like i am going to throw up but burping none stop. My head and ears feels fuzzy and numb and I have really bad headaches. I also take Venlafaxine in the morning.  When i was taken the Mirtazapine, I use to eat eat eat, which i had no problem with since i only weighed 98 pounds, but now being off of it i weigh 92 pounds, no appitte at all, burping none stop and hard time sleeping. What if I get back on it, would that help? I just wanted to know if this had anything to do with it, the only reason i got off of it was because i couldnt afford it at the time, but if it will help me I will get back on it, thats only if it would help. Pls let me know. 
    • Posted

      Hi Allison,

      I had those symptoms exactly... It was terrible. Seem to last about 3 months but I was on Mirt for 7 years.. Cold turkey off it and on to another.. Didn't know if it was Mirt withdrawals or the new ones side effects... Sounds like it was the Mirt withdrawal if you have them too.

      You could go back on them, wait till you feel better again and then taper off slowly. It is the best way but now you've done 3 weeks, you may want to wait it out. 

      I think you can get liquid Mirt which makes it easier to taper than trimming a tablet down each time.

      I think it's the Ashton Manuel... you need to google it.

      It will explain how to do it and why you need to taper and not go cold turkey.

      It truely is horrible hey. First time I've had this trouble swapping Meds.

      I hope this helps but please post again if you need to.

      Yours in sympathy,

      Gina

       

    • Posted

      Thank you so much Gina. I took your advise and it really helped me out a lot. I cant thank you enough. I feel so much better and my life is finally getting back on track. Thank you.

      Allison

    • Posted

      That is wonderful to hear Allison...I'm so glad it helped.. it's good to find out what others have been though and how to help fix it .. I used this forum myself to know I wasn't going mad alone..lol..

      Keep safe and all the very best with your journey

      Gina

    • Posted

      Hi all , my gp stopped my mirtazapine 2 weeks ago without tappering(I was on it for over 3 months) and put me on fluoxetine 10mg for 7 days and after that increased it to 20mg , since stopping mirtazapine I feel constant nasuea , but yesterday on day 13th without mirtazapine and day 12th of fluoxetine Ive been sick , woke up with extreme anxiety and sickness , tremors, cant keep anything down , went to see gp to ask if its side effects of fluoxetine or withdrawl from mirtazapine .he said its neither that is my condition 😳 ive told him I know my body and I know when something is wrong but he just thought I was being drama queen and he wasnt supportive . Prescribed me antisickness tablets and sick note for work. I was on mirtzapine for anxiety but noticed it was making me a diffirent person and I felt numb and more depressed . So now I dont know whats happening , is it fluoxetine or withdrawl or both 🤢

    • Posted

      Hi...

      Had exactly the same problem.. from Mirt to Escitalopram cold turkey after 7 years on Mirt... Went through hell and the Doc said it was my anxiety and me googling side effects..

      I can assure him it wasn't but he thinks he knows better..I'll never do that again without tapering.

      Ive had to change several times over the years and never had such sever reactions before.. unfortunarly, like you, I didn't know if it was withdrawals or Side effects which made it frustrating as I would have stopped the Escitalopram if I'd known...

    • Posted

      Awww bless you , must have been horrible for you feel like this , especially stopping cold turkey after 7 years of taking it. And escitalopram got side effects as well . I hope you feeling okay now x how did you overcome withdrawl from mirtazapine ? How long did it last? Thats what I mean about doctors , they are so ignorant sometimes , we know our body and we know when anxiety is worse than it was befor. Doctors should be more understanding xx
    • Posted

      Hi it has took 3 months I started passing blood in my stools and lost 2 stone in 2 month half a stone in 6 days. So had docs send me for camera tests up and down not nice as couldn't be sedated because I don't have any vain's left. Also had MRI scan as they thought it was something nasty in my bowl or stomach and it ended up it was just withdrawal off that Evil drug matazipean. I would advice anyone with a history of addiction to stay away from this drug. It is a worse cold turkey than any street drug I spent 20 years on heroin and never felt as bad than I did coming off this drug. That also could of been because I live a really good life today have a life that is better than I ever could of wished for. It made me feel like I was dieing but all I will say is it does pass. One day you wake up and it's gone so please hang on in there if you get through this you will get through anything in life. The strength you have is amazing keep going it will be over soon. I think if enough of us put a Partition in to health authoritie there would make doctors inform patients of the serous side effects you get and there should be warnings on packaging about weight loss, the length of time it take you to start sleeping properly again as I sleep one full night in 3 still, then 3 hours at most other 2 nights and this is after over 3 months. Everything else is great just sleep pattern. But you can deal with that once all other stuff has passed keep going bless you, you will do it well done for getting this fare you are strong don't let your head tell you different as if it's like mine it wants to kill you lol.

    • Posted

      Thank you

      It was hard and I thought I'd never be the same again..

      Its been 6 months now and it was really bad for at least 3 months and then I'd get days where it wasn't too bad followed by a couple of horrid days again.. these seem to have got longer as times gone on..

      I now just have off days where I don't feel feel right and can't get anything done but I'm glad to say they seem to be slowly getting further apart.. i've heard it can take a year to get over so I'm hopefully things will continue to settle .

      I hope your going better now.. most will only find the first 4 -6 weeks rough as it takes this long for the new one to work.. the theory is, that this keeps the seratonin in your system but I don't think I'd do itlike that again..There isn't much you can do re Mirt withdrawals except re in state it, wait till you feel better again and then do a slow taper.. if your a couple of weeks in and can put up with the withdrawals then you'll probably want to keep going ..

      See how you go and if it gets worse or not...fingers crossed for you xo

    • Posted

      Thank you so much Paul..

      You brought a year to my eyes because you understand completely..

      It is a nightmare I thought would never end.. I have lost the last 6 months of my life as I couldn't drive from brain zaps and dizziness. The nausea and hot flushes made my anxiety kick right in..the insomnia is bad ..I was getting 2-3 hours sleep a day.. this has improved the last couple of weeks to 4-5 hours but that's probably because I'm on another anti depressant that resets your body clock...supposedly...it has helped a bit..

      I lost 3.5 stone in the first 3 months too.. nothing since then but I couldn't eat anything for those first 3 months I felt so sick..then to get told it was all in my head was like a slap in the face...I'm still taking 15 mg of Oxazepam at night and will deal with weaning off this when I get more settled.. the doc looks at me like I'm a drug addict because I have to take them..

      I'm so glad to hear your feeling better and can't believe you had to go through all that with no sedation!!!.that's terrible..i've had both and I was sedated and still freaked me out ... Your amazing to get on-top of everything and I'm so happy to hear your life is good now.. it takes amazing strength to pull through all that..

      You can tell these doctors do not suffer anything like what we go through..no empathy at all..

      Thank you so much, you make me have hope,

      Gina

    • Posted

      Im glad you feeling better?next time when doctors will want to stop my meds cold turkey I will go mental , I know Ive only been on mirtazapine for 3 months but still get withdrawl or side effects of fluoxetine , just confused as gp isnt helpful at all. I suppouse I need to stick with fluoxetine as it takes few weeks to start to work. Just want to feel like myself again. When I woke up I felt ok then started feeling dizzy and anxious again , and got feeling like my eyes are rolling and horrible headache 😓😐😐

    • Posted

      Hiya Paul , reading your post gives me hope that everything will be okay in the end . Doctors are too sending me for MRI , camera down and up, blood tests . Ive got iron deficiency and had reverse reaction to infusion on top of everything. Just want my life to be the same again when I was happy , feeling okay and when small things were making me content. Now I just live in fear that I will always feel like this , tgat it will never pass and that my life is wasted and that fluoxetine now is going to make me worse and that I dont need it and that im going crazy. Its only bloody anxiety 😯 But on the other side im trying tk tell myself that its only temporary and that it will get better , I hope you feeling okay xxx

    • Posted

      Hi again

      Don't know if this helps, but have now been off 12 weeks. (v quick taper and still taking

      Venlafaxine)

      Horrible withdrawal/anxiety return. Main symptoms physical- shaking, nervy pain, awful muscular stiffness and exhaustion. Some mental tension and confusion too.

      At a crossroads now, as symptoms increasing so more likely to be original anxiety than withdrawal. Need something, but don't want Mirt, sedative or Quetapine (these suggested by Doc)

      For the last week Ive had unbearable neuropathy type pain- like a needle being dragged up and down my spine and ripping up nerve cells.

      God knows what Im going to do, but good luck to you all.

    • Posted

      Hi Steve Im so sorry to hear that you are unwell , I hope it will pass soon, sounds awful 😘I know how you feeling cause Ive got similar symptoms except nerve pain although I had something similar to electric shocks when I was coming off fluoxetine. It might be side effect but I would go to doctors and double check it and then be on the safe side. No need for us to suffer more than we already do with this bloody anxiety and withdrawls. Right now I feel like im swimming , whole body , everything got their own heart beat and this knot in my stomach, lump in throat, stiff neck . Awful. I wish you all the best and hope you feel better soon xxx

    • Posted

      Hi Hun where r u from there is support for u but depends where u live. I can help if in Northumberland but can maybe get u support in other areas. I am in a really good supportive church not a church like people normally think of it's a one that helps the people in local communities looks after each other it is what helped me get away from 20 year heroin addiction. I know it's not for some people but my advice to anyone is don't knock it until u try it. I am part of newfronteers church it was started by one man in his living room 25 years ago now we r in most western country's and a few beyond. It's a different world it changes so many different people's lives for the better. Take care Hun hang on in there u will be ok keep chin up.

    • Posted

      Im starting to lower mirtaz. Have also been offered quetiapine but took it before and hated it. Im petrified of the side effects of lowering, gp says half for one week, then Half again till down to 1.87! Then stop.  I think this sounds very fast having read these pages. Says use diazepam for anxiety.  Dont know what to do for best.  Just hate this drug.
    • Posted

      Hi Paul , Ive been living in uk for the past 9 years and live in North Yorkshire . Community support is most important. Im amazed with you, that after 20 years of using heroine , you stopped. What a strong will 💖well done , its amazing , and now you trying to help other people as well. Amazing xxx thanks to people like you there is always hope xx

    • Posted

      Hi , at least your doctor knows what he's doing and doesnt tell you to go cold turkey like with me. And I went to 3 diffirent gp's 🤔 diazepam helps to take the edge of withdrawl , but I only take it when I cant stand the feeling , like one day I thought I was gonna bang my head against the wall cause my anxiety was so high I felt like my body was on fire . But I only had one such a bad day. Now my anxiety is high but can cotrol it , but stupid nasuea is still there so when I cant take it anymore I sit with my hot water bottle, ginger tea or when its bad take antisickness tablet and lay on tummy. Trembling and feeling out spaced sometimes. But hopefully all will go away soon. Tbh if it wasnt for nasuea and high anxiety Id be at work . Your tappering should be up to how long you were taking mirtazapine for. And crosstappering is adviced when coming off mirtazapine , lowering dose of mirtazapine and starting new antidepressant to avoid side effects and withdrawl. How long were you on mirtazapine for and what dose ? Xxx

    • Posted

      Hope this helps http://www.rcpsych.ac.uk/healthadvice/treatmentswellbeing/antidepressants/comingoffantidepressants.aspx?theme=mobile[/b]

    • Posted

      I have been on a couple of years for depression post surgery, mainly at 7.5 and a while at 15 but it was giving me no help but sleep.  15 gave nightmares.  Lowered down and been bumbling along, psych has tried so many others which were worse.  Now going to try without.  That really scares me. Not sleeping on 7.5 now either.
    • Posted

      Aww im so sorry you going thru this , but maybe diazepam will help you settle a little bit . They both increase each others level and it makes you more sleepy. Anyway thats how it worked with me. Your doc should prescribe you something for insomnia so you dont struggle so much and for the time your body stops being used to mirtazapine. Ive been off it for 15 days and do have sleeping problems and very vivid dreams. But gp didnt want to hear about sleeping pills cause they addictive but yet throw antidepressants on us lol people say diazepam is addictive , ive been taking it before for nearly a year and stopped without problems. Just take it when you need to , its not worth suffering , anyway thats what I started telling myself. And I know that its only withdrawl and will eventually pass. You can do it 😘I just feel sorry for you not sleeping , cause how you suppouse to get better without proper rest. Maybe speak to your gp amd ask for some sleeping tablets, cause it sounds like you need them xxxx

    • Posted

      Ive had sleeping tablets a couple of years ago, managed to get off them slowly and im not sure about restarting them. My hubby is dead against any further meds and wants me to try with his help to get through.  Its all so daunting.  I am using 5mg diaz in night to get back to sleep, gp seems happy with that just now. Just wish i had never seen these mirtaz.
    • Posted

      Yeah I know what you mean. The best thing is to not take anything . Awww bless your hubby , mine is supportive as well and bless them they do want to help and worry about us. Same here , I wish I never started mirtazapine and that was drug of my choice. Starting it was a nightmare for first 3 weeks and coming off its hell. But you will get there and wish you luck xxxxx
    • Posted

      Hi Ann.

      Hang in there Ann... There is an ASHTONS Manual thatmyou can google.. it is very good for tapering scheduals.. it will tell you to never decrease your Mirt more than 10% at a time..you need to take that dose for 2-3 weeks before dropping another 10 %... This will give your brain time to acclimatize before the next drop... It is the kindest safest way to do it..so at 15mg...the first drop should be to no more than 13.5mg..stay on that for at least 2-3 weeks and then drop 10%...this would be about 12mg..then 10.8..then 9.7 and so on...so no more than 10% of the dose at anyone time.. this is good for diazapam too.. itmmakes it much easier.. it takes longer but at least you won't suffer so much... There arenas of making the tabletninto a liquid when you need a smaller dose..please have a look.. I know I will never do I the way the doc said again..hope this helps a bit.. it isn't easy for some of us hey GIna xx

    • Posted

      Hi again...hope your managing a bit better today..it's not nice at all...as if anxiety isn't bad enough at the best of times without all this...

      I came on to see how your going and let you know about this...it won't be much help now although it may give you an insight into what's happening but if you need to change meds again this will help.. I posted it on Ann's reply as well as she can use it if she wants too.. much safer..

      There is an ASHTONS Manual that you can google.. it is very good for tapering scheduals.. it will tell you to never decrease your Mirt more than 10% at a time..you need to take that dose for 2-3 weeks before dropping another 10 %... This will give your brain time to acclimatize before the next drop... It is the kindest safest way to do it..so at 15mg...the first drop should be to no more than 13.5mg..stay on that for at least 2-3 weeks and then drop 10%...this would be about 12mg..then 10.8..then 9.7 and so on...so no more than 10% of the dose at anyone time.. this is good for diazapam too.. it does makes it much easier.. it takes longer but at least you won't suffer so much... There are ways of making the tablet into a liquid when you need a smaller dose..please have a look.. I know I will never do I the way the doc said again

    • Posted

      Sorry Ann at 7.5mg you need to drop to 6.7 first for a couple of weeks.. if you want to do it without Diaz to help you through..you will need to do it gently and safely.. after a couple of weeks it will be 6mg..then 5.5.. then 4.9...so always 10% no more...let me know if you need me to explain anything at all..G❤
    • Posted

      Thank you Gina ☺I feel slightly better today just anxiety and nasuea but im trying to drink loads of water. Noticed tea makes everything worse and I like black tea. Ive been off mirtazapine for 15 days now so there is no really point for me to tapper down now and ive got no mirtazapine tablets left and gp wont prescribe me it cause they will say to wait for fluoxetine to work. They said it to me before when I wanted to do crosstappering . They just dont listen. Hopefully now it can only get better not worse xxx
    • Posted

      Thanks, i have pill cutter ready to start when i feel ready.  I notice othera are reducing mirtaz whilst going onto another a/d. My gp has not done this, she just said try to stop but her taper was too fast.  I am wondering if she thinks i need these at all?   She also told me to take diaz if the effects were getting too much and we can address that problem later.
    • Posted

      Gina, how long did you take mirtaz for and how long did you take to come off it.  I amnot even reducing yet and am having terrible sleeps and nightmares. Just want rid of it.
    • Posted

      Hi Ann..

      I was on Mirt for 7 years and was swapped onto Escitalopram in January this year.

      I was swapped over without any tapering, just cold turkey. One day Mirt and started Escitalopram the next..

      It was really terrible for the first 4 months and then I'd get a reasonable day followed by some more bad days.. I am 6-7 months now and still have off days and some good ones.. it's like you think, oh wow, today hasn't been too bad and then boom, dizzy head etc again.. I think the Escitalopram isn't helping my dizziness and I can't think straight...I also can't remember things from one minute to the next...not like me at all..still can't sleep either..I was getting to sleep at about 1.30-2am and waking at 4am and then awake for 2-3 hours and sometimes I'd fall back to sleep for another hour or two if I didn't have to get up for something...I must admit, I haven't had nightmares like others seem to but I think that's the Escitalopram making me forget as I haven't had/remembered one dream since starting it...

      I also take 15 mg Serapax (sleeping tablet) at night and am on another antidepressant to try and help with insomnia.. slight help and it's helped a bit with anxiety..

      I would never go cold turkey again no matter what the doc says after this..that's why I posted the tapering schedule for you to look at..

    • Posted

      Thanks Gina, i have looked at the schedule. It takes a long time to come off a sall amount (7.5) and with all the other feelings still there.  I dont know if my psychiatrist will let me wait this long and will try to give me another drug instead, but i have tried so many with no good results, cannot stay the course, either hightened anxiety or sleeplessness or agitation.  This is so hard, i dont seem to fit the normal boxes.  So scared i end up in hospital.   Getting appt with psych here is so hard, takes several months. 
    • Posted

      It sure is hard Ann. I wish I could say I was one of those people who sail through swapping anti depressants but I'm not . I too was scared of ending up in hospital.. there were times I should have called an ambulance but put it off because I thought they'd change meds again..

      You really want someone who knows what's going on to see and assess what's needed to do.. I stuck out the escitalapam because everyone was saying it was the least amount of side effects ..I had heaps but don't know how much was the new drug and how much was Mirt withdrawals.

      Another anti depressants would pick up your seratonin levels again but if you don't want to do that it makes it hard.. they usually say to reinstate the original dosage of Mirt until you settle back down and then do a slower taper..it gives your brain a chance to adjust instead of a sudden cut off of the drug.

    • Posted

      Hi

      Me again. I've been off for 12 weeks now. (V quick taper from 15mg)

      More nerve pain than anything. I don't just mean dull pain and pins and needles etc. This is sharp, pressure like sensation. Like someone dragging a knife or needle up and down spine, pulling nerve cells apart.

      Really weird, as never had that before Mirt so suggests to do with withdrawal. On other hand, such a long way into it for symptoms to be increasing like this?

      Thanks

    • Posted

      Hi Ann tell the doctor u would rather do it over two month. Half then half again 2nd month u won't be as bad doing that way.

    • Posted

      Do you want me to reach out and see if I can get you involved with your local new frontiers church for Support.
    • Posted

      Ann if no one is helping print as many of the different people's stories off here and take it to pals they will help you to get theservices to listen don't. give up hun it will get better. Ask your doctor to put it in writing that he thinks it's all in your head tell him to explain y so many of us have gone through the same thing I have a good friend who is a doctor was a shrink told me there isn't enoughresearch done into withdrawal off this drug. Hope that helps.

    • Posted

      Hi Paul , no thank its okay, Im managing somehow for now. But if its going to become more difficult I will let you know. Thank you. You are very supportive 😗

    • Posted

      Feel like printing all these stories of mirtaz lowering as thers loads of them.  Why do drs not believe their patients?

      meanwhile i am going to,try slow taper rather than drs advice of half one week, half again then off.  That would probably send a patient crazy.

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