Mirtazapine withdrawal, how long will this last??!!!!

Posted , 84 users are following.

Help! I slowly tapered off Mirtazapine. It's been 4 and a half weeks off it now and I'm sure I'm still experiencing withdrawal?! I have crippling morning anxiety and zero appetite, the weight gained on Mirt has fallen off! I also feel sick most of the day. I got so down last week that I very nearly went back on it, but couldn't bare the thought of coming off again! Insomnia has just kicked in too. 

I don't mean to post this to scare anyone, as when I was at my darkest Mirt really helped me. I just wanted to know if there's anyone out there going through what I'm going through? Any advice? How long can it last? 

I'd appreciate any help x 

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  • Posted

    Thanks for reply Kirsty,will definitely keep going with with 25%reductions every 4 to six weeks,and even 10% or5% every 4 to six weeks,but will definatley get off this drug.I am taking citalopram 40mg also,which I have been on for same length of time and aim to stay on this drug as no side effects,but nearly six years ago that drug was not enough for severe clinical depression,but think since I'm much more settled,eat well exercise at least 3 times a week,and walk every day,except in the rain.also take 1000mg omega 3 supplements,and a good multivitamin that maybe I will be fine this time.If not will ask to resume dothiepen with citalopram if needed,but hoping it won't be.can I ask how long you have been off mirtazipine? And are you now withdrawel free?

    • Posted

      The doctor did off me citalopram to help with anxiety and withdrawal, it is supposed to be a much gentler drug than Mirt is. So hopefully it will help you with your withdrawal period. I decided not to take anything alongside, as nothing really treats anxiety effectively (in my opinion) 

      I'm now 8 weeks Mirt free, and I would say the withdrawal is pretty much gone! I have no sickness anymore, no bad tummy, I still have anxiety, but I did before taking it! The feeling of doom has gone too, that was horrid. And the nightmares are definitely less! I did read it can take 6 months to come out of your system completely, but I'm not sure how true that is? 

    • Posted

      That is so good to hear! So pleased for you,and thank you for replying,always good to hear that withdrawals do eventually subside.
    • Posted

      Not a problem at all, I know how hard it can be, and can feel like a never ending road. But there is light at the end of the tunnel, just keep going! Stay as busy as you can and even though you may feel sick try to eat a little bit as it will help. Loads of water too! X
  • Posted

    Hi kirsty did your side effects eventually go...I'm on day 7 off no mirtazapine and the withdrawal is unbearable 😢

    • Posted

      Hi Pamela, yes they did, but I won't sugar-coat it, it was a very long road. For a month I felt awful, absolutely awful, with "waves" of severe withdrawal. I'd say it took roughly 7 weeks for this to start easing off. It's a tough journey, but it can be done! X

    • Posted

      Hi Kirsty, still at 3.75 and holding as i am having nausea days and odd tummy ones sometimes.  Horrendous migraine last week.  Still sleep not so good and confused REM dreaming with me.  Going to ask again about liquid, will pay if necessary.  Do find depression a bit worse, is that normal, scared to fo down a dose in case it affects that.  I just wonder if i am ever going to be well, a lot of people on here are on mirtaz with another a/d and i am not.
    • Posted

      I am nearly at the end of withdrawal but all the symptoms i have, nausea, diarrhea, nightmares, insomnia, anxiety and worst of all still depressed are still with me.  Are you suffering the same having come off?  Does your dr offer you a new anti dep tomhelp?
    • Posted

      I am in a bad way with mirtazapine slowly dropping. Have now started to get old symptoms of anxiety and depression back five weeks since lowering.  Have you needed to increase?
    • Posted

      Hi Pamela would just like to know what your last dose was before you tapered off? Or did you just come off.and if so from what dose.
  • Posted

    Hi kirsty

    how you doing? You must be coming up for three months off mirtazipine now,would be good to know how you are doing,and that withdrawel symptoms do settle.

    really hope you are feeling better.

    • Posted

      Hi! Thank you for asking after me 😊 YES they do settle!! It's a very long road, but they absolutely settle, i now know that all of the sickness, feeling of dread and doom, paranoia were all the withdrawal. I'm so glad I kept going and didn't go back on it!! I still have anxiety, but I've had that since I was 11 so I miracle cure is going to happen there! 

      How is everything going with you? 

    • Posted

      i am waking shaking, nightmares, black thoughts, depressed,but agitated.  All these were my original,symptoms but were slightly more under somtrol on 7.5

      i dont know if this is them coming back since its five weeks now lower and its worse each week.

      mirtaz never really took them away, just  dulled them.

      do you think this will pass or i need to increase again

    • Posted

      I think you may need to go back to your GP, and get advice there. I never went up and down doses so can't advise much there-sorry. Maybe you do need to have something else to help you? X

    • Posted

      I am seeing consult next week but i just wondered if you suffered depressive symptoms on the reductions, or was it mainly nausea, headaches or what?  I have had them but the feeling down was unexpected. I havent gone up a dose at all, just down them.   Its just im wondering if i should be feeling a bit better now, i had been hoping for that
    • Posted

      I did feel days of utter despair and depression. Way worse then how I was before even stating the med! I've heard this isn't an uncommon side effect. It too a long time for me to start feeling better, and that was after I'd tapered off completely x

    • Posted

      Hi kirsty

      I am at 18.75mg,where I have been for two weeks,and now the nausea,sweats,tinnitus etc have settled.thank you for asking.I will stay at this dose another two weeks,then drop to 15mg,where I will remain until after Christmas and new year period,as I really don't want to feel really unwell during this special family time,which I love.

    • Posted

      I think that's a very sensible plan. I came off just before going on holiday as I really underestimated the withdrawal (partly because of doctors) I was an anxious wreck for most of the holiday. The way you're doing it, will mean you're at a level place to be able to enjoy Christmas 😊

    • Posted

      Did you suffer from nausea as well.  I am waking with it some days and cant eat till teatime.  Its like being pregnant!
    • Posted

      Oh god yeah! The sickness was awful, I could barely eat for weeks! And yes, if I didn't know for sure that I wasn't pregnant I would have been buying a test!!! 

    • Posted

      Hi, I have been reading posts referring to mirtazapine withdrawal.  You seem to have done well so i would,like your opinion. Never tolerated more than 15 so went down to 7.5 for over a year, not better just manageable.  Psyhc tried some others which made me worse. Says i have anxiety but i definitely feel so depressed on waking.  I am at 3.75 now and feel so anxious some days, others very low, dreaming bad dreams. Is this the lowering. I am hoping to get down to 1.88 after xmas but the way i feel i dont know if i will get to xmas without a major downer.  I can get up and dressed by lunchtime, feel very anxious, take diazepam then try to get on with day. Bed by 9pm. No life really.  Many on site say coming off is bad but what i dont understand is will this get better once im off it, does anyone know, i dont want to spiral down ito deep depression.
    • Posted

      Hi Ann

      I really feel for your suffering.I am not a medical professional,but just my own honest opinion,is that from what you have posted that this drug is doing nothing to help you.I know how scary it is tapering,as withdrawels are  pretty awful,but you are clearly suffering right now,and if it were me I would want to find a drug or treatment that would enable me to live life once more.withdrawels do settle down eventually (only from my own experience they have) then if you need another medication or treatment then you can seek this.I would make appointment with GP or psychiatrist and explain just how bad you are feeling,and maybe it's possible for you to be put on another medication or treatment that will allow you to live life once more,whilst you are tapering down.I will taper again come new year,as awful night terrors are no longer an option to put up with for ME that is,but I too am scared of depression rearing its ugly head,but you never know it may not.Good luck whatever you decide.

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