Mirtazapine withdrawal - light at the end of the tunnel
Posted , 12 users are following.
I would like to share my withdrawal experiences in a bid to encourage all of those having a hard time coming off this drug.
I was prescribed mirtazapine for sleep issues in April last year. I was assured by my Doctor that they are 'totally non addictive' and that I 'could come off them at anytime' This was appealing to me as I was desperate for a solid 8 hours sleep (I had been sleeping around 3-4 hours a night for 2 months)
Please note, insomnia was the only reason for taking these tablets. I didn't feel depressed, just desperate and anxious for sleep.
My sleep improved dramatically from the first tablet I was sleeping for at least 9 -10 hours each night. At times I'd feel a little groggy but most of the time I felt refreshed and I was so relieved to be sleeping well again.
About 4 months later, my sleep pattern started to become very erratic. I'd sleep for 10 hours one night and then I wouldn't be able to sleep at all the following night. I contacted my Doctor and she advised me to double the dose. I didn't double but I did increase it from 15 mg to 22.5mg This seemed to do the trick. Apart from the occasional bad night I was sleeping well again.
My sleep continued to improve for at least 3 months, until my sleep became erratic again. The mirtazapine had obviously pooped out and I had become too tolerent for this dose. Of course my Doctor advised increasing the dose again, but I had wised up this time. I wasn't going to set myself up for another fall, I couldn't keep increasing the dose for the same thing to happen again.
I decided to taper off the medication. I had no idea of the misery and suffering that lay ahead. I would go up to 3 consecutive days without any sleep at all. Not even the dozing type! Instead I would have heart palpitations and repetetive songs playing in my head throughout the night. (I later realised this is a common withdrawal symptom) I had it really bad.
I felt completely depersonalized. I didn't have any interest in anything and I could barely muster up the energy to leave the house. I have my own business and this really suffered. I was a wreck, a complete zombie. I'm ashamed to say that there were times that I felt suicidal. What had this drug done to me?
I was able to seek comfort from other peoples experiences on this site. I also contacted the charity CITA, I spoke about my troubles and the state that I was in. It was a relief to do this, as I tend to keep things to myself so nobody around me would've known the extent of the problem. They helped devise a plan to gradually come off the medication altogether. It was reassuring to know that my symptoms were very common and that the situation would improve. They weren't able to give me a timeframe as recovery varies for different people.
I had spent 5 months on a slow taper from November - April. I cut the tablets up into smaller pieces and remained on 2 mg for a month. I then continued to miss one 2mg tablet over 7 weeks. So I'd take 7 one week, then 6 in a week, then 5 etc.
I have been off the tablets completely for over 6 weeks. I'm not out of the woods yet but I feel so much better. I sleep between 6.5 - 7 hours each night. I have been taking 100 mg of 5htp capsules an hour before bed.I could only take these after I had quit mirtazapine completely in order to avoid the risk of seretonin syndrome.
My advice to anyone suffering from withdrawals is know that the symptoms will pass eventually. stay strong and do the best you can to get on with life. Try not to dwell on the withdrawals and know that each day you're getting furher away from mirtazapine. There will be set backs, that's part of the withdrawals. Just accept it and keep moving forward.
Good luck to everyone trying to come off this drug. You wil get there!
2 likes, 58 replies
Louisaluvsrio scott10262
Posted
I had to stop taking it after a year because I had nightmares and felt lethargic the next day and was not as active.
Glad you have weaned yourself off them.
susansasha scott10262
Posted
Calmer susansasha
Posted
Mirt WD messes with your sleep a lot, just want you to know you are not alone and that this is a common symptom, maybe ease your concern.
Trying not to worry about not sleeping is hard, especially in the middle of the night, but if you can say to yourself it will get better and try not to let the worry take over and create more anxiety (as hard as it is) i skey - some nights will be worse than others - try to find a simple breathing relaxing/self hypnotism for yourself that you can do anytime - when the anx' hits you, day or night may be of great benefit.
Wushing you well.
susansasha Calmer
Posted
scott10262 susansasha
Posted
It's very common for the symptoms to come back in waves. You'll have a few days when you think you're over it and then it strikes again. This can be very demoralising, but I can assure you things will get better
Seek comfort on the fact that if you have a bad night or 2, you are likely to fall into a deeper, more restorative sleep on subsequent nights. This is probably what you experienced for a few days before last night.
It has been 7.5 weeks since i took my last 2mg tablet. I am still getting withdrawal symptoms but they are happening less frequently.
Get up early and make the most of your day. Fresh air and plenty of activities throughout the day can do wonders for sleep.
susansasha scott10262
Posted
Calmer susansasha
Posted
Hope you had a better night x
peter86299 scott10262
Posted
scott10262 peter86299
Posted
I started off at 15mg and went up to 22.5 mg for a couple of months before going back to 15mg.
I used a pill cutter, which helped me to cut it up with a degree of accuracy. Others have tapered more precisely by reducing their dose in liquid form.
If I were you, I would reduce the dose by 10% and give it 2 weeks or so to see how you feel before deciding whether to reduce it again.
All the best
peter86299 scott10262
Posted
Calmer peter86299
Posted
Hope you don't mind me jumping in here, just want to reassure you that those dreams are a common side effect of Mirt', longer you're on it the more that fades. Also the doctors you speak of, and my doctor and most folks on this forum say the same - they seem to know very little of how to wd from this Mirt' AD ... gather all your info on this forum, take what you feel comfortable with, think and plan long and hard before trying to wd if you are in the midst of a lot of stress.
Wishing you well Peter, Calmer
peter86299 Calmer
Posted
When I eventually get down to 7.5mg/1/2 tab will remain on that for@least 1 month and longer when I reduce further-please feel free to jump in whenever as i appreciate your above comments-Like you just want this out of my system ASAP-i WISH YOU WELL ALSO IN THIS CONTINUED FIGHT FOR WELL BEING-TAKE CARE-Rgds=Peter+.
peter86299 Calmer
Posted
peter86299
Posted
Calmer peter86299
Posted
I have sent you a private message, hope this is ok.
Wishing you well fellow sufferer
peter86299 scott10262
Posted
On Saturday and Sunday evenings I reduced and took only half a tab 7.5mg to see how I felt and felt ok but thought yesterday i felt made the wrong choice and last night Monday went back up to 15mg- to wd much more slowly and today do not feel great-would this short period of time of only 2 days @the lower dose and then stepping back up to 15mg have such an effect-I think you have previously commented not to do this-presume now in a period of days before i stabalise again and will feel better-take care Peter+
peter86299 Calmer
Posted
Calmer peter86299
Posted
I understand your anxiety and worry about waking at 4.30 but going back to 15mg now, in my opinion, would be a mistake. You say you went to 13.1 mg 3 weeks ago and have been ok on this ... I think this is the answer for now for you. Stay at 13.1 mg for a few weeks - until you feel stable again and get your confidence back.
I think you are saying
15 mg to 13.1 mg EVERY NIGHT for 2 weeks (to last Thursday)
Then 11.25 EVERY NIGHT since
I think dropping the dose should be much less severe - as the CITA plan you have.
Going too fast is not for you Peter, I think you have said that you have tried twice now to withdraw - so maybe being kind to yourself and following the well-trodden advised plan will help you more in the long run.
I understand also if you feel so desperate that you must go back up to 15 mg, this may or may not cause you more anxiety after getting down to 11.25, that's why I think it's best for you to now stick to 13.1 mg.
How do you feel about that?
I will check in again tomorrow - I am not very good in the evenings, I feel I need to switch off from all computer, games, texting, multi-tasking etc ... it prevents me from getting to sleep, which is one of my problems too !
Wiahing you well Peter.
I have also sent you a private message.
peter86299 Calmer
Posted
last night took 15mg tab to see the reaction and had worse sleep-hardly slept @all-but will drop back down again tonight and re-instate to 13.1mg-presume/hope this 1 night@higher dose will not cause any great problem-what do you think
i took the 13.1mg from 14th july till 29th july every night
then 30th 111/4mg-felt slight wd so re-instated back to 13.1mg
then 31st-1st aug-2nd aug and 3rd aug back to 13.1mg
and last night the 4th aug took 15mg-hope this will now not undo and affect all the previous nights@13.1mg-what do you think .Apart from
Sunday and Monday nights waking@4.30am and last night hardly any sleep all other nights had been reasonably ok.-Would appreciate your kind comments-please keep well-thks+rgds=Peter+++.
peter86299 Calmer
Posted
re your private message many thks but not received-take care-rgds=Peter+++.
peter86299 Calmer
Posted
My initial plan on reducing was as follows-REDUCING FROM 15MG
13.1mg for 31days-currently in this period-
11.25MG 31days 1/2+1/4 tab
7.5mg for 31 days 1/2 tab
3.75mg for 62 days 1/4 tab
with no weekly/daily alterations/reductions@all
or do you think it is better to keep to the CITA METHOD BASIS THE 15MG CHART WHICH SPREAD OVER 14 WEEKS
SO ON next monday 10th and for the next 2 weeks would remain on 13.1mg
and when the 1st day to reduce would be in week 3 -the thursday of that week would reduce to 7.5mg only for that day and continue with the other weeks and the days to reduce as per their chart
then after the 14th week period ends would then start on the chart basis reducing from 7.5mg-What in your opinion is the better plan-Sorry to go on about this-thks for your continual time and patience on this-much appreciated as always-Best Regards=Peter+++.
Calmer peter86299
Posted
I have e-mailed you - did you not receive the e-mail?
I think the above ratios are a bit too severe - I think you could get away with 13mg down to 11mg but not the others below. I would say stick to the chart I sent you yesterday.
If you feel anxiety is getting to be a problem stay at the dose you are on at the time, do not go up again, but remain there until you feel settled or stable again.
Wishing you well Peter
peter86299 Calmer
Posted
no did not receive your e/mail and chart -can you kindly please send it again and the chart-maybe this got directed into the company's spam a/c? and got deleted?
so will revert back to 13.1mg tonight-do you think taking the 15mg last night is likely to do any harm/damage?
Wishing you well also-take care-Rgds=Peter+++.
Emis Moderator comment: I have removed the email address as we do not publish these in the forums. If users wish to exchange contact details please use the Private Message service.
http://patient.uservoice.com/knowledgebase/articles/398331-private-messages
peter86299 Calmer
Posted
will revert back to 13.1mg tonight-only hope that by taking 15mg last night this will not cause any slight problem-what do you think?
You too keep well and take care-rgds=Peter+++.
Calmer peter86299
Posted
I have resent the e-mail, could you please reply with anything else with a personal message, think the moderator doesn't like personal info on here.
I think you will be absolutely fine going to 13.1 but as suggested, I would only take 13.1 for 2 nights out of 7 nights for the first 2 weeks. After that follow the plan x