Mirtazapine withdrawl after only one half dose!! how long will it last?

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Hi i have been reading all these thrads on here about mirtazapine and its withdrawl symptoms and it really is a nightmare drug.

I literally only took a half dose last weekend (7.5mg) and within one hour I had a headache, dry mouth and worst of all i had really bad aches in my joints that pretty much prevented me from walking, every time i tried to bend over to get something i felt like i was going to fall over. i also experienced dizzy spells like motion sickness without the nausea. This was last Saturday, sunday was just as bad.. all day in bed (after these side effects i was determined i would not touch this medicine again), on monday thankfully the pains in my joints subsided a bit and i was able to walk again with relative ease but the motion sickness/dizziness started to get worse, since tuesday the motion sickness dizziness (feels like i'm going to lose my balance) has gotten worse and stayed the same.

I have no idea if these are withdrawl symptoms? i literally only took one dose of 7.5mg and that's it nothing else! i spoke to my gp various chemists and manufacturers of the drug and they all tell me that it should be out of my system now and they don't know what the issue is and that withdrawl symptoms shouldn' occur because i only took a small half dose!

but reading the threads on here i'm seeing lot of you have similar symptoms but to a much greater degree.

How long do these withdrawl symptoms last for?? I would never have taken this poison drug had i known all these effects would occur. literally as i write this i feel as if everything is swaying slightly, loss of balance. since yesterday i've developed some mild muscle twitching.

they just said i was hyper sensitive to this drug hence why i have these side effects adn that the half life is realtively long 40-65 hours noted, im a young male 33 so i shouldn't be having these issues.

I have't found a thread where anyone has come off mirt and no longer feels any withdrawl symptoms. has anyone been off mirt and managed to eliminate all withdrawl symptoms or is this going to affect us for years to come?

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  • Posted

    Sounds psychosomatic to me. 7.5 mg is very low doage anyway. I would give it a longer try.
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    • Posted

      No offense, Nick, but is someone has a reaction at that low of a dose, I would not have him try it longer. Try something else. Mirt. is usually a last line of defense for depression or anxiety, I think, mostly due to its side effects and withdrawals.

      Even if it IS psycosomatic, so what? It made the man sick and he still is. This can be a nasty drug. And I know it can be a life saver for some, but I don't think Pete qualifies for that.

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    • Posted

      Every psychiatric drug has its side-effects and calling it a "nasty" drug doesn't help.

      It would depend how unwell someone is. If there symptoms are not very great then is it worth the side-effects - if these are they.

      Clearly reading a website like this can put in to someone's mind a dread of taking the drug.

      Pete, were you given the datasheet concerning the drug. If not you can find it on patient.info.

      patient.info/medicine/mirtazapine-for-depression-zispin-soltab

      Have you got a Care Coordinator? You can ring the Emergency Team.

      Of course, if you have only taken it once you are not going to have withdrawal symptoms if you stop taking it. So you can speak to your Care coordinator on Tuesday or, if not, you should speak to your GP and/or your psychiatrist.

      The side-effect that I am sure of was that after I stopped taking it - after 2 years? - pains and aches in my joints stopped. I had been having difficulty getting out of bed.

      But I have bipolar/depression and I do have to look after myself but I am almost well.

      There are generally other drugs you can take - when I came off Lithium I was given a choice of 2 drugs. The pdoc gave me the datasheet and left it to me to choose.

      I asked to come off Prozac because it effected my libido.

      I had a course of ECT when I was in hospital - as a last resort.

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    • Posted

      I said it "CAN" be a nasty drug. I didn't say it was. A very distinct difference. All ADs can be nasty. Some folks cannot take them.

      This man is obviously very sensitive to mirt. as he only took one and has been ill since. It DOES happen with even one dose if you are sensitive to it.

      I agree with the rest of your adviceconfused

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    • Posted

      i dont think this is psychosomatic because i only found out about the withdrawl stuff the day after it started going dizzy on tuesday, by then it had already been 3 days since i took the dose. within one hour i was having the side effects which made me realise that something wasn't right.

      im surprised myself how 7.5mg would cause such an adverse reaction.

      i remember 24 hours before i took a nortryptiline 10mg and 2 days before i had some citalopram but i didn't think these drugs would interact esp if i left 24 hours between them.

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    • Posted

      im surprised myself too that i would have what would be withdrawl symptoms after only one dose.. it's really strange. if it's not withdrawl symptoms of dizziness and motion sickness how can it still be side effects from the drug in my system it's been 7 days since i took it on Sat yet the effects im having are like those expericing withdrawl.. i know it has a relatively long short life meaning 50% of th drug could still be in my system up to 65 hours max after so if it takes another 65 hours to halve again to 25% i would be coming off that on to 12.5% now but chemists told me it should be fully out of my system. it's all very confusing why i'm having such adverse effects coming off it only takign it once.
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    • Posted

      Your body may just have had such a terrible reaction. That does happen, and it will take a little time for your body to readjust, but get yourself some motion sickness medicine at the pharmacy and see if that helps.
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    • Posted

      Kathy

      Are you a GP, psychiatrist or pharmacist? What are your qualificaions for supplying this advice? You don't supply some personal experience of how X helped you but rather seem to pull rabbits out of the hat.

      What are you going to suggest next?

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  • Posted

    I would think you should be okay fairly soon. You are hypersensitive to it, and it may take a bit longer for your system to get back in balance. So sorry you are going through this, but, take heart in that you only took it once.

    Perhaps taking some Magnesium, Omega 3s and a B complex will help you rid of what remains. Keep us posted, Please!!!

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    • Posted

      does mangnesium omega 3s and b complex help with clearing the withdrawl symptoms?

      i was thinking i should go see my gp after easter for motion sickness medication to stop the dizziness. how long is this going to last? sad

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    • Posted

      Pete, not sure where you live, but the over the counter medicine for motion sickness helps a LOT of people. You should give it a try. It may help right away. Can get it at your local pharmacy. Good luck and let us know.

      The supplements help your body to readjust after taking mirt.

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  • Posted

    I've been on Mirt 30 for 1 yr. It is a very effective antidepressant . Yes it does come with some pretty horrible side effect as I state, however I have recovered twice on this drug, lost weight on it and came of it successfully. This drug although works quicker than other antidepressants however can take up to 3 months to wrk effectively. I am back at wrk full time , no side effects and feel brill. Ps I've been on every anti depressant x
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    • Posted

      how long did the withdrawl symptoms last before you went back to normal and had no more dizziness?

      i am on 4th day of dizziness since tues and it has gotten slightly worse since then.

      is it expected i[m going to have 3 weeks of this withdrawl symptom even though i only took one 7.5mg dose?

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  • Posted

    my doc told me these were not addictive i stopped taking them for 2 days on second day having panic attacks in bed bad head i had aswell very nasty meds im on 45 im going drop down try get off these not good for you at all 
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    • Posted

      I told my pdoc that it was preventing me from peeing. He told me to come off it straightaway - since then it was probbaly something else.

      But the unintended effect was that my muscular pains stopped - a doctor friend of mine told me that it was well known for its musculo-skeletal effect.

      The GP should be monitoring this kind of thing. It wasn't the only reason that I changed my GP but it was one reason. If I reported anything to him he didn't make links, IMH, to, say, my drugs.

      But in conclusion I had no withdrawal symptoms, but the pains in my thigh and pelvis ceased - it really seemed like a miracle to me. I was actually able to get out of bed without holding on to something. It was like a miracle cure.

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