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Mouth sores after taking Methotrexate

Posted , 7 users are following.

amkoffee
amkoffee

I have been plagued with sores on my tongue ever since I started taking Methotrexate. My doctor warned me about this and I asked her at the time if I would be more prone to it since I have burning mouth syndrome. She didn't think so. Here's my question. Have others had this problem and solved it by taking the med by injection? I have appointment with my Dr in two weeks and will talk with her of course but want to bounce this off of all of you first.

0 likes, 10 replies

10 Replies

  • EileenH
    EileenH amkoffee

    Posted

    You ARE on folic acid as well aren't you? To be taken on days you DON'T take the mtx. If the dose you start on isn't enough - you need more. 

  • MrsO-UK_Surrey
    MrsO-UK_Surrey amkoffee

    Posted

    Are you taking Folic Acid?  If not, your GP should prescribe it  to help offset this side effect whilst on Methotrexate.  Also, do try to avoid toothpastes containing SLS and those containing Triclosan.  I recommend Sensodyne.  Wine can also aggravate the situation in some people.
    • amkoffee
      amkoffee MrsO-UK_Surrey

      Posted

      Since I have burning mouth syndrome I can't tolerate strong mint flavor that is in most toothpaste so I get mine from the health food store. I checked and it says it does not contain SLS. But there is no mention at all of Tricloscan. So it either isn't in it or there isn't enough in it for them to have to list it. And as for the folic acid I am taking 1mg daily. Someone told me the other day that that was probably not enough.

    • EileenH
      EileenH amkoffee

      Posted

      It obviously isn't if you are getting mouth ulcers - most people I've heard speaking about it take more than that.

  • LayneTX
    LayneTX amkoffee

    Posted

    I take prescribed Leucovorin Calcium 5mg once a week.  Doctor said if I didn't that I'd get mouth sores. 

     

    • amkoffee
      amkoffee LayneTX

      Posted

      Interesting. I'll have to ask my doctor about that. I take a calcium supplement but I'm assuming this is different in some way?

    • EileenH
      EileenH amkoffee

      Posted

      "Leucovorin is a reduced folic acid. Leucovorin is used in combination with other chemotherapy drugs to either enhance effectiveness, or as a "chemoprotectant."

    • amkoffee
      amkoffee EileenH

      Posted

      Yeah I looked it up after my reply. So I just called my rheumatologist and they're gone for the week and their message said if I had any questions that couldn't wait to ask my GP. LOL. So I called my GP and am waiting on a reply. Ooh I know I could have waited until after the new year but I just wanted to make sure I'm safe to take more folic acid with all the other drugs I'm on.

  • Daniel1143
    Daniel1143 amkoffee

    Posted

    After I read the side effects, the first thing I did was get off it. Beyond that, I found no positive benefits to Methotrexate.
  • FlipDover_Aust
    FlipDover_Aust amkoffee

    Posted

    I've been on MTX for just over a year now. Right from the start I was taking 15mg of folic acid for the three days following my MTX dose. No side effects from the MTX that I'm aware of other than being able to lower my pred dose dramatically - which was of course, the raison d'être!

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