My vocal is down for 20 days. Is it related to Thyroxine dose

Hi Sumonayeasmin, the synthetic and other prescription thyroid medications are not quite the same as our human thyroxin, so they can result in an initial or long lived immune response. This could cause additional inflammation to your thyroid. Some people find this goes away after a while, some don't. Please read the insert in your medication about side effects, or go to the online manufacturer's site.  You will see that one side effect if thyroid medication is thyroid disease.

There are many posts here on thyroid health, do read through them, as many of us have struggled for years and have researched methods and lifestyle changes for preventative treatment.

Please understand that the traditional treatment of thyroid disease is to do nothing until your thyroid is so bad that surgery is the only alternative. If you read through the posts here, you'll see that health following thyroid surgery is not optimal. So you'll want to look into dietary and supplement changes to help curb the progression of the disease. Many folks here have had success with curbing the disease, and even remission. It's a lot of work, but worth the effort to save your health, as thyroid disease is VERY serious and affects every aspect and function of your body.

I can't imagine your goiter turning a tough texture that quick either..  I wouldn't jump into surgery that quick.  You should definitely give it some time and get a second opinion to make sure it is your goiter that is actually affecting your vocals. Most of us have goiter's also, and I know, for myself.. never had problems with my vocals, hopefully we'll hear from other's.  The only thing I was ever bothered with, was wearing tight cloths around my neck.  But, everyone has different sized, shaped goiters.  They should be able to tell if it is affecting your vocals from an ultrasound.