Need Advice - is continued flare-ups part of the Allopurinol experience?

Posted , 7 users are following.

I am 51 and have had gout for 4 years with intermittent attacks. 5 months ago I started Allopurinol and am at 300mgs now. Went from UA 8-9 to around 5+. I don't drink and lost 50 pounds. My diet is good (plain oatmeal, fruit, greek yogurt, cottage cheese, eggs,  almonds, 6-8 oz chicken, vegies, bean/vegetable soup and sweet potatoes). I stay under 1500 calories a day. Got to lose 30 more pounds.

 I still get flair ups - every 10 days or so. Its like a 4 or 5...I can walk (limp) on it but its a nagging pain in the same joint (big toe).  I take colcrys and Naproxen at first sign of pain to keep it from getting worse. It usually fully goes away in 2-3 days.

I just started drinking cherry juice, and apple cider vinegar, but it doesn't seem to make a difference.

1) Is it normal to have these flair ups on  Allopurinol ongoing? do I just consider this part of my life now? ask for an increase to 500mgs? or ask Dr for something else?

2) what else is there to take? I have no side effects on Allo other than these flair ups.

I know some of you have it worse. But I cannot plan ANYTHING (gym, social, outings) because I simply don't know if ill wake up limping.


0 likes, 7 replies

Report / Delete

7 Replies

  • Posted

    Unfortunately I don’t think there is a straight answer to give you. From my experience of this forum, everyone is different, reacts to different medications and diets. Personally, I began using allopurinol on its own and suffered disastrous side effects. I now take no medication and ha e been symptom free for weeks, well, about 98% better anyway. If I suffer a brief attack of gout then so be it, but it has to better than the debilitating pain I went through after taking allopurinol. Get well soon!
    Report / Delete Reply
  • Posted

    Check out all the references on this site and others to celery seed.  People are reporting that it has really worked for them.

    Also are you on diuretics or other medications that can cause gout?  If so you may have to work with your doctor to find alternatives.

    Good luck.

    Report / Delete Reply
  • Posted

    I think celery seed extract make work the best based on what I have been reading.
    Report / Delete Reply
  • Posted

    I dont take any other medications. I do take a mens multi vitamin. Wonder if there is something in there to worry about.

    What horrible side effects do you get from Allopurinol? My Dr told me all i had to worry about was short term possibility of flare-ups until the Allo worked the UA out of the body.

    Report / Delete Reply
  • Posted

    Changes in uric acid levels cause flare ups and this is for both raising and lowering. That's part of the reason you're not supposed to begin taking Allipurinol for the first time while you're having an attack. Typically, it takes a few months for the drug to equalize levels. I would caution against increasing the dosage. This drug is no joke.

    I can't take it because I have liver and kidney disease. You may want to have your blood-work done with a kidney panel just to make sure everything is okay there. Poor functioning kidneys do not do a good job with excreting uric acid. As a matter of fact, under excretion is responsible for 90% of all gout cases, while over production of uric acid causing attacks is at 10%

    Cherry juice doesn't work for me. I've tried ACV, baking soda, lemon water, everything. Nothing really helps, but I normally only have attacks once a year. Coincidentally, in the spring when the weather gets warm/hot. I know dehydration is a major trigger for me, so I drink a lot of water.

    Good luck, but like I said, I would not start increasing that dosage yet. Give it a little more time to work its magic and, in the meantime, stay hydrated.

    Report / Delete Reply
  • Posted


    Allopurinol is a wonder drug for many of us.

    It is critical to note that you MUST be patient with it and above all do NOT stop taking it.

    It can take up to a year to settle down.  I have been gout free for about 5 years thanks to drug.

    Ensure that you are talking to a medically qualified doctor who specialises in this area.  A GP will often not be fully informed.

    But allopurinol is often(usually?) a fantastic solution.

    My specialist (medical expert) advised me that lifestyle/diet is FAR less important than taking the drug.

    Works a treat for me!


    Report / Delete Reply
  • Posted

    I completely agree with sabre0492 regarding Allopurinol - it’s no joke and has known side effects, especially at doses greater than 300mg. I much prefer the all-natural approach (diet and herbal remedies). One other option is turmeric, and there’s a uric acid lowering product from Botanic Integrated (found on Amazon) that’s patented and has research showing amazing results toward lowering urid acid levels. It might be worth trying for some folks. Good luck! 
    Report / Delete Reply

Join this discussion or start a new one?

New discussion Reply

Report or request deletion

Thanks for your help!

We want the forums to be a useful resource for our users but it is important to remember that the forums are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the forums is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.

newnav-down newnav-up