Need advice on mirt side effects.

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Hi, would like to ask any long term users of mirtazapine do you still have side efects and if so what are they. I dont know if my many symptoms are being made worse by mirtazapine. Also would like to ask how long usually does it take for side effects to wear off or become less severe. Will be very grateful for any advice.

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11 Replies

  • Posted

    hi carole lack of motivation can be a side effect. what dose are you on? and how long have u been on mirtz?  julie x
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    • Posted

      Hi. Julie thanks for replying. I have been on 15mg for six weeks, the problems are bad pressure in head and ears. Pins and needles in face and feet. Internal vibrating feelings. Extreme fatigue. I have a long term illness and am bedridden anyway, but wondered if any one else has same side effects. Doctor wont change them as iv had every anti d going over the last 17 yrs and not had much success.
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    • Posted

      by six weeks should be in your system, i take 50mg sertraline in morning and 15mg mirtz at night, the mirtz counteracts the side effects of serts and the sertraline counteracts the side effects of mirtz, you shouldnt be having these side effects ,so tell your gp how they are making you feel after 6 weeks u shouldnt be feeling this way x
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    • Posted

      Hi, Julie. After week 4 i told my gp about these effects he told me to increase to 30mg but i am too scared to in case i get worse. The mirt have decreased my anxiety and depression somewhat, but the side effects cause me to have anxiety. I was the same with amitriptyline but after 4 years i just became so low and not wanting to wake up any more i came off them cold turkey and was very poorly thats why doc gave me the mirt. Last resort he said as i had horrendous side effects with th ssris xx
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  • Posted

    Carole, as Julie states, my motivation has decreased. I often wait to the last minute or beyond to do something that should have been done. I was never a big motivator, but the lack of it seems to be everyday. Seems strange, mirt. helps with my mood but not motivation.

    Your side effects may outweigh the benefits. You may want to make an appointment with your Dr. again.

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  • Posted

    I was on 45 mg for about 6 years. I was waking in the morning with what I would describe as a hangover. I asked the doctor if I could get off the drug since I had been on it for so long and thought that I may no longer neede it. We did it this way: 30 mg x 2 weeks, 15 Mg x 2 weeks, stop, I immediately started having mostly gastrointestnal issues, and, felt basically sick; sort of like flu symptoms. I called my GI specialist, and she said that I had been taken off too quickly, and told me to go back on the 15 mg for 2 weeks, and then 7.5 mgs until I felt ready to try it again, and we would see what happens. 8 months taking the 7.5 mg, and tried again. Same withdrawal symptoms came back. I am now on 7.5, with the possibility of trying again with half of the 7.5 mg. You are asking about side effects, well they differ from person to person, as does the time that it takes for your body to adjust to them. I would just like to make this point. I am on 2 heart medicines, Protonix, Lipitor, & Synthroid. I don't want to be on any of these. But sometimes you have to take medication to give you a better quality of life, or in some cases, life itself. Diabetics don't give themselves insulin shots because they like them. If I have to take Remeron (Mirtazapine) for the rest of my life, which I hope is quite a while, as long as I feel better on it, then so be it. Getting off of a medicine is always best if it is good for your health, as all medications are chemicals that make changes in our bodies. But just because one person feels it best to wean off a medication, that may not be in another's best interest. When I started on Remeron, it was to give me a better quality of life, in other words, to make me feel better. If it takes 15 mgs of Remeron to help me feel better, I consider myself fortunate that the drug exists. Yes, it is a powerful drug, and yes, it isn't easy to stop when you want to. I feel that the doctors prescribing it should make those facts known to their patients before giving it to them. I sincerely hope that this has been helpful. I worked in a hospital ER for a number of years, and for those who receive comfort in knowing that you aren't in misery by yourself, well you aren't. There are all kinds of withdrawal symptoms, from quite a number of drugs, and I wish you luck in finding a physician that will assit you in chosing your medications wisely! Beat of Luck!
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    • Posted

      Hi David,

      I have found your post extremely interesting and helpful. I,too, have been taking mirt 45mg for 6 years and am attempting to come off it. I am currently down to 15mg. Since being on the 15mg I have had some wd symptoms of muscle aches, nightmares, some insomnia (whole nights sometimes) and recently terrible lethargy and daytime tiredness. I totally agree that doctors should make it known that some people may have some difficuties in withdrawing from these drugs so that an informed choice can be made before starting on them. I have gained information from these forums that, once down to 7.5mg, it is a good idea to obtain the liquid form of mirt and then reduce the dose slowly by 1mg at a time thereafter (under guidance from your gp) to avoid any further serious wd.

      Best wishes x

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  • Posted

    Carole, thanks for your reply. I have learned something new today. I know that you could get the dissolving Soltabs, however, I didn't know that it is available in liquid form. But, some medicines are available in other countries that we can't get in the US. My son has done quite a bit of traveling in Europe, and graduated from the University of Salamanca in Spain. According to him, he could get quite a few different meds for allergies, some of them OTC, that he can't get here. Iwish you luck in your endeavor. My doctor put me back on 7.5 mg today, and if I feel decent while on them, I'm not sure if I will try this again. As stated in the previous post, I tried twice already, I was put on this medicine by a doctor who has retired, and my GI doctor took over filling it at that point. She says that they have been prescribing it for years as a anti-nausea drug, so I guess that it makes sense that several
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  • Posted

    Hi Carole, I have been on mirt for about 5 years now alongside with other drugs it keeps my Bi-polar disorder at bay I find I never experienced any side effects apart from a occasional metalic taste in my mouth.  The meds I take are quetiapine and Epilim the Epilim is a dual purpose drug for me as I use it for its anti-convulsant properties and it is a great mood stabalizer  
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  • Posted

    I've had no problems ongoing side effects it just gives me a better sleep. I think it's different to what you were prescribed it for in the first place. I was first put on it for a deep depression (fourth in my adult life I'm 62 now) prescribed with 3 other drugs originally, but down to this and escitalipram 2 years later. I. The only side effect was when I had recovered after 6 months was a bit slow in getting 'going' in the morning, however it's difficult to say how much this was the remnants of the depression. I'm not anxious and depressive person quite the opposite but probably genetically liable to develop depression.
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