new to MTX questions

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Hi Everyone,

I recently began weekly low-dose Methotrexate for Sarcoidosis. I'm currently doing 5mg a week and will soon be worked up to 15mg. I know that MTX can be hard on the liver and I'm concerned about accidentally doing something that might damage my liver or throw off my monthly blood work. I was hoping to just run a few substances by the forum and get a yay or nay on whether they would be okay while on MTX. I apologize in advance if this has already been covered elsewhere on the forum.

  1. Valerian root tea.
  2. Neurotransmitter supplements like Gaba or 5-htp
  3. Over the counter pain medication like Ibuprofen or Acetaminophen. If those are a no go, are there any safe alternatives for the occasional headache?
  4. Biotin supplements.

This isn't specifically a liver question, but I've also heard mixed things about caffeine and MTX. Any thoughts on that would also be greatly appreciated.

Thanks so much!

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