Help please! Would be v grateful for any advice. After 20 + years on seroxat GP suggested transfer onto mirtazapine. Despite tapering this has failed spectacularly with appalling insomnia, anxiety and mental turmoil. Now being advised to transition back to the seroxat in order to relieve these truly frightening symptoms. I now seem to be in an impossible situation....do I go back to seroxat knowing that I probably can't face trying another withdrawal attempt (this is the second) and that it is probably becoming less effective for me and/or doing me other damage? Mirtazapine seems to be almost as bad so I don't think there is any point in staying on that. My history of recurrent depression means I probably need to have some kind of long term medication so rejecting all antidepressants is also hugely scary. Any thoughts please? Thanks.