Non type specific igG test. Help understanding results

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I was just hoping other people could help me figure out my blood test results. My doctor order a non type specific igG blood test. My result was .76. I know with type specific igG test sercoversion is a worry if you have a 'high negative'

This is my result at 8 weeks post exposure and it is a high negative but I'm wondering if it's high because it is not type specific so in a way it's higher because it is combining both hsv index values of antibodies that would normally be lower for example

Hsv 1/ .40

And

Hsv 2/ .36 and together equal the .76 value I got.

I am doing another test soon this upcoming week sometime but once again my doc order non type specific. It seems to be difficult to get the type specific. Thanks for your help

0 likes, 5 replies

5 Replies

  • Posted

    Ask Felis Cactus....Very knowledgeable
  • Posted

    I've been trying to read online about non type specific but can't seem to find the answers. That's why I thought I'd try here
    • Posted

      Felis will probably see this and help wink give it a bit.
  • Posted

    Thanks, Nikki! smile

    I'm afraid that few people test by non-type specific IgG these days, and it is no longer recommended by major health authorities, so there is little online about the test and how to interpret results, etc.

    There is a reason why it is no longer commonly used or recommended, and that's because it is less accurate than type-specific tests, plus it is important to know type. False positives are more common with non-type specific tests. Less sure about false negatives. In any case, HSV experts seem to view it as useless as IgM testing.

    Even so, the good news is that you tested negative. However, you also tested at 2 months. While many people will have produced detectable antibody levels by then, some may not. If I were you, I would ask your clinic about the type-specific test, ask other clinics if yours can't do it for whatever reason, and retest by type at 3-4 months for certainty.

    Not quite an answer to your question, but hopefully still somewhat helpful.

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