Olmesartan no effect on blood pressure

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I have been on Olmesartan on and off for several years. Apart from suffering the usual side effects, it has no effect on my blood pressure.  Unfortunately, I can´t tolerate the normally added HCT and react badly to calcium channel blockers too, I was, so to speak stuck.  Dr at the end of her tether.  Everthing else of this group (angiotension II....) have the same effect, ie. nil, only the side effects.  I should add that I have been given Emconcor, betablocker, with it, which made no difference. Most of the time I do feel dreadful - nausea, stomach pain, headache, you name it.

I don´t really expect a reply, or advice - just wanted to let off steam.  I do believe that the pharma industry writes their own praising info sheets, and the medics prescribe because it sounds so wonderful.

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  • Posted

    How high is your BP when left untreated and do the side effects then go... just in case it is something else causing it

    You need better advice than you get from a GP. Ask to be referred to a Hypertensnsion Referrel Centre. Google the words to find one in your area.

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  • Posted

    Elke, I'm surprised that if Olmesartan has no effect on your blood pressure you have been taking it "on and off for several years".  I have a similar experience with Losartan when taken on its own but fortunately haven't experienced any discernible side effects.  It's only when they add another pill to the mix that I always get such horrid side effects.  The beta blocker, Bisoprolol, was the last pill to be tried but it didn't make a scrap of difference to my blood pressure but did cause a drop in my kidney function which caused a scare.  I am aware of sevral people who take Losartan which does work for them in reducing their blood pressure and it is the one BP pill that my pharmacist has said he hears the least complaints about from his patients.  Worth a try for you perhaps even though it is an angiotensin II receptor antagonists.  Because one in the same class might not work, it doesn't mean to say the same will apply to another.

    With regard to calcium channel blockers, they should not be given to anyone who has narrowing of the arteries to the kidneys

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    • Posted

      Thank you so much, Mrs O-UK Surrey. Most helpful, and I will certainly suggest the Losartan to my GP next week. They have given me Olmesartan (here in Spain Openvas, no generic) because they seem to consider it the best in this group. HCT cannot be added because I am allergic to sulfonamides and, as mentioned, CCBs cause terrible side effects (feel sick all the time), although very effective. I am aware that Angiotensin II... combined with a betablocker is not a very good combination but the betablocker prevents palpitations

      When taking the Olmesartan only, 40mg, BP shoots up to 180 in the morning and only occasionally will go down to about 135/88 pm. Thanks again.  I will report....

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  • Posted

    Google berberine and Nih and see all the great metabolic things it helps with... I started a while back after hating Ca channel blocker (who thought interfering with EVERY muscle fiber would be good idea ????), and a few others.. (diuretics caused continuous tinitus in left ear... every day/night... ugg..). Essential Hypertension - a cop out.. Maybe its too much stress/coffee/Cortisol/Adrenaline, but there is no diagnostic code for overstressed....

     

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  • Posted

    Thank you,  Derek, and the side effects are definitely caused by the blood pressure medication(s). The Olmesartan was actually prescribed by a specialist several years ago who did, or had done, numerous tests which were all ok. However, I noticed right from the start that (a) it had hardly any effect on BP and (b) caused stomach upsets, head and muscle aches and a few others. Saw GP, and then the song and dance started:  first CCB, wonderful effects, after 2 weeks really unbearable nausea and tachycardia. Back to O., and then second CCB, back to O... And so it went on. Fact is that the antiotensin II... as well as the AEC don´t do anything to my BP, diuretics are out because I am allergic to sulfonamides and the very effective CCB - see above. I am now resigned to it, am taking felodipine and put up and shut up. Olmesartan was acceptable but after all, it is the BP that matters and as I am a "senior" patient, O. and the like do not act well for us, which is well known but not it seems amongst the medics...

    Thanks again.

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  • Posted

    Hi all,

    I am coming back to my previous "cris de coeur" about Olmesartan etc. Dr took me of Felodipine (side effects intolable) , and I am now suprise surprise back on Olmesartan 40 plus Bisoprolol 5 mg, plus, for anxiety Lexotanil 2 x 1.5mg, as my high BP is "de basa nerviosa" so I was told years ago.  Very high mornings, levelling out pm

    Has anyone out there experiece with a similar combination, ie angiotensin II blockers and betablocker and how did they get on? Would be very interested.  As I said before, all the other groups are a NONO for me because of side effects.

    Thank you all out there.  

    (GP is of opinion that the Openvas (original) , ie. Olmesartan, is the most effective in this group...)

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