One person's journey with sertraline

I also stopped this med a little over 5 years ago, primarily due to being hard-headed. I'm considering going back on, but am on the fence about it. It will be interesting to see your progress. Thanks for sharing your experience.

Still Day 24:  No headache.  Depression is mostly gone, after a hard morning.  I notice colors and depth to flowers.  (When people are in oxygen deprived environments, colors become more muted.  When given oxygen, the colors return to normal).  I am seeing colors I remember from childhood, as well as a better appreciation of depth perception.  It seems like my mental "tunnel vision"  is opening up to a wider view of the world.  Maybe I can live a normal life!

I have been  successful on Zoloft, now Sertraline, for over 20 years , but now after dealing with multiple aging parent issues, 87 -year -old mother with  Alzheimer's and 97-year -old father with limited  physical ability, I have relapsed into depression and anxiety.  I also retired from a high level professional position.   Lots of transition and challenges.  Blood test revealed that I do have MTHFR C677T gene mutation (homozygous ) which can affect the ability to process folic acid which is linked to increased risk for depression and anxiety.  I started taking  Deplin a month ago and felt better during the first week or two but now feel worse emotionally.  I do yoga, eat healthy, etc.  My psychiatrist might try something to supplement Sertraline with another drug.   I would appreciate any feedback if you have had any success in adding any drugs or supplements  to the Sertraline prescription - especially if you have been on Sertraline for an extended period of time.  Keep on striving for peace within you.  

Yay! I made it to the four week point where I am supposed to start feeling the benefits. I'm spending week at a family reunion (social anxiety issues) in a two hour time zone difference. (off body schedule). I have no anxiety issues, even though sleep is disrupted. No headaches, no heaves, appetite is returning. No depression when I awake!!! Congratulations to me, I pushed through. I do find myself gritting my teeth often, something I never did before, but it's only a minor annoyance, like if I had a bad cut on my leg; it doesn't affect my movement, I am just aware it's there. I still feel precarious, but there's no anxiety or depression issues. Thank God.

Day 29; So far, it's a two exedrine migraine pill day, but Zero social anxiety. No depression, no dry heaves - I' ll take this anyday. It's amazing since I'm at extended family reunion, with time zone disruptions. I am getting used to having physical depth perception back. I didn't realize I hadn'thad it for years. Real life looked more like a TV screen. The 2D vision returned when a storm came in, and the light was more muted. Interesting. I can't get over the No social anxiety issues. I am still mentally on high alert in terms of carefully watching my boundaries, eating and sleeping enough. But this is unique; no crying silently in my pillow multiple times during the day....