PAE and Subsequent Prostatitis

Posted , 10 users are following.

Question for those who have had PAE or are very knowledgable about it. PAE works by embedding microspheres in arteries/blood vessels that supply blood to the prostate. The microspheres significantly reduce the amount of blood reaching the prostate and this causes prostate cells to die and the prostate to shrink.

It is well known that antibiotics have a difficult time reaching the prostate. So if a man has PAE and then has subsequent prostatitis caused by bacteria, won't the antibiotics have an even more difficult time reaching the prostate? Could the PAE make it almost impossible to cure prostatitis caused by bacteria using oral antibiotics? Would a man in this situation require direct injections of antibiotics into the prostate? Is that even an option?

0 likes, 28 replies

28 Replies

Prev
  • Posted

    When the blood flow is cut off, the blood vessel and that area which the blood vessel serves dies. So you are left with only areas with a normal blood supply. The idea that a healthy part of the prostate is permanently blocked is incorrect.

    • Posted

      TG

      Thank you for that comment. That is true. If this procedure killed the prostate you would have more problem they shrinking it. It would also kill anything that is attach like the nerve bundles I don't think we what that

      Have a great weekend.........Ken

    • Posted

      This makes sense. Also, the same dead areas would not be a place where bacteria would likely survive.

  • Posted

    Oral antibiotics have difficulty getting into places like the prostate which is why the Fluoroquinolones (e.g. Cipro) are a popular choice for this problem. They have a fluorine molecule which greatly increases the tissue penetration (apparently).

    The problems with Cipro etc. have been written about on these discussions already (or see the Fluorquinolone antibiotic pages), but also bear in mind that a meta-analysis of available data showed in 2012 that both Cipro and Trimethoprim (an alternative AB) were 'no better' than placebo. It has also been stated that 95% of prostate problems are non-bacterial. (If I give links this will be moderated but ask if you want them).

    Doctors are very keen to give out oral ABs without ever finding out if the problem is bacterial or not. Only if the problem isn't resolved do they decide it was non-bacterial after all! This is back to front medicine, and, unfortunately for many men, the lengthy course of Cipro taken 'just in case' ruins their lives. (And they still have a prostate problem to deal with on top!).

  • Posted

    The areas that dont get the blood die off and get reabsorbed by the body, This shrinks the prostate. The Dr's know exactly where to do this. The prostate keeps growing also. I've heard of PAE being done twice. . PAE is done to treat BPH not prostitis so thats a separate issue. But I'd rather have a smaller prostate with prostitis.

    • Posted

      Ozone is a gas, was commonly used to treat infections until penecillin developed. These days it's still used because of antibiotic-resistant infections. As a gas it can be injected IV or infused into the rectum or fills cavities or inhaled.

  • Posted

    I've had BPH for 15 years. My dad and grandad each had prostate cancer. I've having PAE next week. Yesterday I had a flow dynamics procedure. Then computer problems meant they lost the data and I had to go through it all again. It wasn't as bad as fractured ribs but it was a close second. It's been 15 years of always needing to know where the nearest toilet is so I'm hoping the PAE helps that.

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.