PE and Rivaroxaban
Posted , 2 users are following.
I'm a 59 y/o male who was diagnosed with PE in left lung on 17Jan confirmed via a d-dimer and chest CT scan - I mistook my symptoms for muscle pull over night and I left it for 24 hours before going into ER to get it checked out at my wife's insistence - symptoms had almost dissappeared within 48 hours and had i not gone to ER when I did then i wouldn't have bothered and I'd have been undiagnosed( undiagnosed PE's are quite comon according to my Doc). Anyway they put me on Rivaroxaban and after 5 days I started peeing blood (haematuria) over a 3 days period which freaked me out big time !! I've had no recurrence now for 5 weeks and my urine is seems back to normal . However they were't sure if the haematuria was due to the Rivaroxaban or someting else - so I've underwent a variety of tests including haemo/bio , psa , dre , kidney/bladder ultrasounds and a cystoscopy which have all been clear - I have a echocardigarm scheduled for next week afterwhich I hope i can get back to living a normal life.
I got back on my bike today for the first time since and I did 15 miles and felt really energised afterwards. I do have some reservations on being on Rivaroxaban long term as there is no antidote (unlike warfarin) - but i'm probably going to be on it for 6 months - I will just need to go easy on my bike and make sure that I don't fall off - LOL 
1 like, 5 replies
-.a-way_forward ChooChoo
Posted
http://www.nice.org.uk/guidance/ta256/documents/atrial-fibrillation-stroke-prevention-rivaroxaban-final-appraisal-determination-document2&sa=U&ei=3bf5VLyVI4TCPKWygLgP&ved=0CBAQFjAA&usg=AFQjCNEYGXVNSJP09b95QVSU1Tee7Hwlcw
-.a-way_forward ChooChoo
Posted
I was told Rivaroxyban has a half life of 12hrs - I guess that's the antidote- simply stop taking the med...
ChooChoo -.a-way_forward
Posted
the half life is generally dependent on age/health of an individual - so during hours 13-26 whilst it's still active in your body is still heck of a long time during which time you can bleed to death. Thx for your advise which i wont be taking
-.a-way_forward ChooChoo
Posted
well it seems like our lives are in our hands - budget permitting...
I am not competant to give advise - nor would I feel compelled to, however I have found a pdf document on the net - I do not know if it is a credible document, from a credible source...(i will post a link and can peruse whilst its being moderated) here is an extract...btw it gets quite complicated and I do not like needles or the sight of blood....so oral administration for me...
__________
Guidelines for Warfarin Reversal with Vitamin K
Reversal of warfarin is complex. Guidelines published in CHEST 2004 provide greater understanding of how to manage warfarin reversal using vitamin K. Below is a summary of these guidelines.
Introduction
When the INR (International Normalized Ratio) is in therapeutic range and therapy is interrupted, the INR will return to normal in 4-5 days. Treatment with vitamin K substantially reduces the INR in 24 hours. Since the absolute bleeding risk is low even in the presence of an excessively prolonged INR, patients may be managed by interruption of warfarin therapy and monitoring frequently, provided the patient is not at high risk of bleeding or already developed bleeding.
Warfarin Resistance
When large doses of vitamin K are administered, warfarin resistance may occur for up to a week.
-.a-way_forward
Posted