Post-treatment Lyme Disease

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Good morning, I am a Mexican student in UVM, I would like and would appreciate if you could answer this question. What causes post-treatment Lyme disease syndrome?

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3 Replies

  • Posted

    The bacteria which have survived initial treatment. The body reacts to the bacteria and it is this reaction which causes the symptoms.

  • Posted

    i know this is a late response but check out ILADS.org. it has good information. You could still be infected despite what your tests may show. Also check out Dr Ying Zhang's research out of Johns Hopkins. I'm in a similar situation as you. I was treated three years ago and still have "flares" that can be awful! Im meeting with a Lyme Literate Dr in a couple of days. Hopefully ill improve.

  • Posted

    About 10% of patients with Lyme disease continue to experience musculoskeletal pain and cognitive dysfunction after recommended antibiotic treatment. This condition is called post-Lyme disease syndrome (PLDS) or post-treatment Lyme disease syndrome. These two terms are used interchangeably. The pathogenesis of PLDS has been controversial. The hypothesis that patients with PLDS may harbor hidden reservoirs of Borrelia burgdorferi after their initial antibiotic treatment is difficult to accept. The prospective, double-blind studies contradict this point of view. Also, recently published research applying xenodiagnosis to PLDS supports the opinion that PLDS most likely has an autoimmune background. Lengthy courses of antibiotics are not justified in patients with PLDS because of the lack of benefit, and they are fraught with hazards. Most patients with PLDS recover from persistent symptoms with time. However, it can take months before they feel completely well.

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