PPI and osteo arthritis

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Hi I've really painful hands with lumps in my fingers since I was 32. I haven't been diagnosed but I think I have osteo arthritis like my mother. She has had operations to her hip , knees and toes. She lives with pain every day. Now recently I had gallbladder surgery two months after had a baby, but the pains got worse. I am taking lanzoprazole for heartburn  for a month and my hip and my knee start aching. Does anyone know if taking this kind of PPI can make this condition worse? I am only 39 and worried about all that has been happening with my body.

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  • Posted

    hI Leni.  Firstly, it's important to get it correctly diagnosed as different conditions react differently to various treatments.  Painful swellings on the hands can also be due to a form of gout and this can be kept under control by different meds.  I was taking omeprazole, similar meds to yours for acid cause by NSAIDs for pain, I dont recall it causing aching joints though.  The aching may be inflammation related to your hand pain, so it's definitely worth discussing it with your doctor as there may be a simple way of reducing your inflammation and also your pain.  I have OA in my thumb joints following years of tenosynivitis and it's killer at times but I only have slight swelling of the joint when it's very inflamed, which is why I believe you really should get it properly diagnosed as it may not be OA.  Good luck.
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  • Posted


    I think the first thing you need is a correct diagnosis then you will know what you are dealing with.

    I've been taking omneprozol or lansoprozol.....it changes occasionally for about 5 years now. Its prevention because I take Naproxen.

    I've never heard of it causing pains

    Different meds can affect different people in different ways.

    Are you in the UK....Go to your GP, get a referral to the hospital and a correct diagnosis.....

    Hope you find out something definite


    Eileen  UK

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