Prednisolone plus ibuprofen
Posted , 12 users are following.
I’m on 6mg prednisone after reducing from 25 mg some months ago. Last night I took 1 ibuprofen tablet for head ache and I am almost pain free today. Why can’t I take ibuprofen daily.
0 likes, 27 replies
karenjaninaz leef
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leef karenjaninaz
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Anhaga leef
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ptolemy leef
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Bethune leef
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leef Bethune
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Bethune leef
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leef Bethune
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jacqueline02102 leef
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I checked with our pharmacy here in the UK and plain paracetamol ( nothing added) is ok to take with Prednisolone.
BettyE jacqueline02102
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I'm sure that is the case for almost everyone but when my GP asked me to try it ( explaining that if it eased the pain I was still feeling as I reduced the pred. then the pain was not PMR..... I think I've got that right ) the result was to make me feel so ill and gave such alarming LFT readings that I was fast tracked to see the liver man at the hospital. Within ten days of stopping the paracetamol my readings were back to normal.
Whether that was the combination of Ped. and paracetamol was never indicated. It was just flagged on my " do not" list.
Don't want to be alarmist but be aware.
EileenH leef
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NSAIDs rarely have a good effect in PMR so whatever your pain is now it is possibly not due to PMR. If you want to try taking ordinary pain killers paracetamol/Tylenol might be a better alternative - although it can do a number on your liver if you are unlucky and use it long term together with other drugs that stress the liver. Especially, I should add, alcohol.
leef EileenH
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leef EileenH
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EileenH leef
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No - that WASN'T what I said, I said it was possible that the pain you have at present MAY not be PMR which was why it responds to ibuprofen. As we reduce that allows in other results of aging and the normal twinges of advancing age, OA and so on. Plenty of others on the forum will say the same.
Your rheumy has some strange ideas - why stick you on methotrexate at this stage? Even if it IS LORA, low dose pred is an accepted form of management and it would make more sense to see if you are able to reduce the pred dose without it and without the other things, whatever they are, worsening.
But above all - you have only been on pred 8 months, the likelihood of being off pred in the next year is quite low, less than 1 in 5 of PMR patients are able to get off pred entirely in 24 months so you would be unusual. I hope you are so lucky - but don't be disappointed when it doesn't happen.
I have a friend whose GP put her on to ibuprofen for her PMR. After 3 doses she was in A&E with a gastric bleed. Don't think that ibuprofen is a safer alternative to be able to stop taking pred. It may not be. As for methotrexate - at this stage in the context of PMR, on just 6mg pred, it doesn't make much sense. I would certainly want a lot more proof it was RA before I went onto it for life.
Anhaga leef
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I believe that all anti inflammatories can have an effect on PMR but it could be so insignificant when your inflammation is raging you don't notice it. When I was undiagnosed I always felt better, although only marginally, when I had to take aspirin for a headache. What I later learned was PMR eased slightly. I never started taking any painkillers regularly because nsaids, including aspirin, interfere with cartilage regeneration so are bad for people with osteoarthritis, as I have. I think it's entirely possible if you are still on a low dose of pred, which isn't quite enough, that the addition of the ibuprofen was just what you needed to deal with that day's worth of inflammation. Personally I would stick with enough pred to manage PMR and save the other medications for when they're needed for something else.