Prednisone long term use and adrenal insuffiency

Posted , 8 users are following.

After long term pred use i am now seeing my first known major prednisone side effect other

than weight gain ,skin bruising etc.

A couple of years ago i had a major flare and with a few hiccups it has taken me about

18 months to get under 7 Mg daily. At 6 1/2 Mg i started to feel unwell, so upped the dose

to 7 Mg

This seemed to clear things up but lowering to 6 1/2 , again i was unwell. I see sawed the dose for some time before seeing my GP, who said she suspected my adrenal glands were lazy , if not completely wrecked.........

Recently i had a tummy X ray and CT scan for an unrelated problem.

Amongst the report was a reference to my adrenal glands that said............

Both adrenal glands are moderately to severely hypoplastic.......

My GP explained this by saying your adrenal glands are stuffed through

long term prednisone use............

So now i have to take for life , a dose that keeps me feeling ok........

This i have to determine myself and for a start have settled on 7 Mg.

At this dose the PMR will , hopefully , look after itself.

Maybe if i had persevered with lower doses for shorter times ,things

may have turned out different , who knows...................

Yeah , so that is where things are at the moment, time will tell...........

1 like, 21 replies

21 Replies

Prev
  • Edited

    I think im a very similar situation to you. I have been on pred since 2009 and am unable to rid the pain. So I have now decided to up my dose by 1 mg a week until i feel better. Decided I will control this myself.

    • Edited

      It may be better to zap the pain with an increase of 5 mg (or slightly more depending what your current dose is, how bad the pain is and how long you've had it) and then carefully step down to find the lowest dose which will work. undoubtedly somewhat higher than where you are now. That's the standard increase we recommend. Stay at the effective increased dose for a week or so to make sure all the built up inflammation is dealt with.

    • Posted

      GDay Pam,......On the odd occasion that i see my rheumy, he just says, you know how

      you feel, so adjust your dose to suit yourself.

      So unless it is something new to me i just do that...........

    • Edited

      Pam ,But.....in saying that.......Anhaga has some good advise.

      Not much point in slowly raising the dose to try and find a better

      level.

      That just does not work..........it needs a bit of a kick to get the

      inflamation under controll...............then drop back to your

      desired level and gauge it from there..............

    • Posted

      Exactly. A short spell on a higher dose may in fact mean less total intake of pred than slowly increasing to find best dose. 😃

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.