Progesterone intolerance and Mirena coil

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I wonder if anyone can give me some advice. I have been on Oestrogen only for 2 years which was incorrectly prescribed since I still have a uterus. I was told I needed progesterone. I started taking Utrogetan and reacted badly to that. I was told this is the most natural of all progesterones. I was sent to a specialist GP who told me I needed the Mirena coil. After 5 days I feel terrible - nausea constantly, pain in my vagina and even nerve pain in my bottom, terrible headaches. I want the thing taken out as soon as possible. Does anyone have any ideas? I feel so well in myself on the oestrogen only, but obviously I can't continue without the progesterone. I feel absoultely dreadful and so down about this. I just want my life back!

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4 Replies

  • Posted

    I had exactly the same thing happen to me... I reacted badly to Uterogestan, then hated the Mirena - felt much better literally as soon as it came out (it really was an immediate improvement).  I then went for about 9 months with no progesterone at all. Felt much better like that but the dr wasn't happy.  I ended up having a total hysterectomy so that I could take the estrogen on it's own.  I opted for ovaries out because there seemed to be a definite cycle to my feeling very fatigued and aching etc etc.

    Even that hasn't been plain sailing though... The estrogen that I'd taken when I still had ovaries and uterus, worked better when I actually had ovaries.  I think something the ovaries produced now seems to be 'missing', since I had them removed.  The supplements I use - estrogen and testosterone - don't quite replicate.

    I'd say consider a hysterectomy, keep the ovaries.  BUT, the downside of having the uterus out, for me, is that orgasms feel very different - not as nice...

    • Posted

      I'm so pleased I'm not the only one with these problems. I would honestly consider a hysterectomy in order to get through this nightmare! I had heard you could have the womb lining removed, but nobody has suggested that to me. It seems crazy to have a hysterectomy just in order to take oestrogen only, but I can't see any other solution! I'm really grateful to you for replying.
    • Posted

      Not fair, is it?  The upside of your ovaries removal is that you won't ever get ovarian cancer, and there are medical studies which say that ovaries and breast cancer are connected, therefore almost totally reduces your chance of breast cancer too.  No worries about uterine problems either with the hysterectomy.

      Not all oestrogen therapy is equal.  Luckily I was put straight onto oestradiol implants, then had to move to oestradiol patches when they stopped making them, but now found a compound chemist who makes the implants and am back onto those.  Treading warily as my first one did not work at all and I became oestrogen starved with all the consequences of that.  (Got my patches on standby!)  It may have been incorrectly inserted (not into enough fat) as my gp had not done one before.

      I also use vagifem every 2nd night and oestriol cream on outer bits.  The oestriol cream is supposed to be collagen repairing and strengthening, so may help with the orgasm problem, if you don't already use it.  I have not found it necessary to use testosterone.

      I have been using all this for 26 years now due to early surgery.  I don't plan to stop using them.

  • Posted

    Im in US. Texas. I've been on Bio-identical hormone replacement therapy since Dec.2014. Had hormones tested via saliva. Was real low on progesterone an low on the two estrogens. Testosterone was ok. So had my own prescription made with what I was low on, not a one size fits all pill or cream or whatever. Its a vaginal suppository. After using it for 8 months I started having bleeding. Had uterine biopsy an it was normal an pap was normal an vaginal sonogram was normal. So one of the estrogens was lowered. Been on new prescription for 3 an half months an no bleeding. I was 46 when menopause hit unexpectedly. Never had female problems. Also had depression and anxiety an palpitations. Palpitations stopped 2-3 months after starting Bio-identical. Still struggling with depression but under alot of stress rt now which could be NOT helping. Caregiver for 80 yr parent's an father is non-compliant with everything. But my skin hasn't plumped up. But I know i don't drink enough water an have fibromyalgia an take Ibuprofen alot. Find out about Bio-identical hormone therapy.

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