PSA Spike 1.77 to 6.96 in a year

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Hi All,

Last year 6/2015 my PSA was 1.77. In March this year I had a Colonoscopy and doctor found that i have an enlarged prostate. This month i had PSA check and went up to 6.96. I'm wondering if the rapid rise in my PSA 1.77 to 6.96 in a year is somehow related to enlarged prostate or something else. Should i be concerned here? I'm 49 yrs old and so far have no symptoms of prostate problems like urgency or pain or etc. i'm going to seek urologist soon.

Any advice or information or what i should do next is greatly appreciated.

Thank you & God Bless

david

0 likes, 23 replies

23 Replies

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  • Posted

    David,

    I am a proton therapy advocate. My PSA went from 2.1 to 4.2 in 2 years. My urologist felt a nodule on my prostate during an exam and ordered a biopsy. It was cancer. I went through proton therapy treatment. It was painless and I have had no side effects. That was 5 years ago this past April and I am an advocate for proton therapy as well as work at the proton therapy center in Oklahoma City where I live. YOU DEFINITELY NEED TO SEE A UROLOGIST ASAP! Any time your PSA doubles from the time of your last reading it is a red light warning. Don't put this off.

    • Posted

      Hi Nathan, Hope you got mates rates for your treatment as you work in a proton therapy centre....Here in Australia, Proton machine planning commenced here in 2006, and our first machine's maybe operating in 2018...Science tends to move slowly downunder.

    • Posted

      This is my UPDATE.

      I just had a 3T mp-MRI done by a very well-known West Coast Radiologist, Dr. Robert Princenthal, and the results are below in exact wordings. The conclusion is that I have a prostate inflammation and it is likely causing my PSA to spike. MRI is about 90% accurate so there is a 10% chance PCa can be missed. I plan to be vigilant and will have a 3T MRI done once a year (at least until my PSA goes back to normal score). My next PSA test is Jan 4, 2017. Thanks.

      ================

      IMPRESSION:

      No unexpected high-grade tumor suspicious nodules. Diffuse decreased T2 signal seen throughout the peripheral zone associated with mild areas increased perfusion but no restricted diffusion or focal nodules. Those findings are OFTEN associated with benign inflammation or prostatitis.

      The transition zone was unremarkable and show normal morphology within stromal nodules. No significant extraprostatic abnormalities are seen.

      PI-RADS: 2/5

      Despite negative MRI findings, there is a 5-10% possibility that prostate carcinoma may be present. The decision to proceed to standard biopsy should be based on clinical data and discussions between the patient and his physician.

      ================

    • Posted

      David, Good news that following the cipro your PSA is reducing and the MRI supports the diagnosis of a sick prostate, rather than it having PCa. 

      I am on my 4th week of a 6 week cipro course. I then have a PSA and PHI test as well as usual urine test. Hopefully, the PSA is reducing from 13. Otherwise, I see little choice than a biopsy will be required. 

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