questran-anyone have stomach ache after starting this?

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Hi, I have colitis (controlled at present), ibs-d, & just been diagnosed with bile acid malabsorption & been prescribed questran(colestyramine). I started with 1 sachet daily 1st week, then 2 sachets daily (am & pm) from week 2. In the leaflet it does say side effects can be more wind(tick), bloating (tick), constipation (not had) & sometimes stomach ache(tick). & these usually disappear with continued use of this medicine. Although there are some positive effects, I have almost constant stomach ache from the waist down, like a dull ache which worsens & eases without reason but never completely goes. I suspect this is just a temp side effect, but wondered if anyone else had this when starting questran (colestyramine)? Did it disappear the longer you continue with this med? If so, how long was it before it eased off? I was hoping to go back to work in next few weeks, but am worried about this dreadful stomach ache hindering matters. Any comments, advice, experience of this welcomed..

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  • Posted

    I'm going to be starting on questran in the near future as I have been diagnosed with bile acid malabsorption as a side effect of my cholestectomy (how ever you spell it) so would also be interested to hear people's responses and how you are doing looloo x
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    • Posted

      Hi emmacarrie & maggie. i started 1st wk of questran 1 sachet day, & for several days had a bit less diarrhea, & stomach went really quiet calm-no gurgling,squeaking, fizzing , bubbling like it normally does, so was quite hopeful of further progress when going upto 2 sachets daily. sadly the progress didnt continue, & i had worse stomach ache than before & bm's not much better. I read the leaflet & it said for diarrhea normal dose is 3-6sachets daily, so I thought nothing to lose by going upto 3 a day(i'd done wk2 on 2 sachets). Today I have done 2 sachets together am, & 1 sachet pm. The stomach ache has greatly reduced & i've only had 2 normal bm's today & no diarrhea, so perhaps I was prescribed too low a dose. I will carry on with 3 for a week & see how I get on. Maggie- thanks for your advice on the alternative if I don't get long term relief from questran. I went for this one first purely because I can take my other meds 1hr before or 4hrs after, the colesevelam is 4hrs either side & I thought this could get tricky timing wise especially as I am hoping to return to work soon if the meds help me enough. If I cant get on with the questran I'll have to try the capsules. thanks again.
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  • Posted

    I was diagnosed with bile acid malabsorption recently after suffering IBS(D) for over 20 years.  My Connsultant said it is caused by having my gall bladder removed and the bile acid dripping stright into my lower interstine and speeding up the evacuation of food recently eaten.  I have been prescribed Colesevelam (625mg) daily after my evening meal. What a difference it has made. Feel like I have my life back.  Having researched the subject it seems that tummy cramps/wind are quite common with Questran.  if it doesn't settle soon I would ask your conssultant if you could change.  It has made such a difference to me. Good luck


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