Rage/Anger

Posted , 62 users are following.

Have now been on Mirtazapine for 7 weeks and am seeing GP tomorrow as I am not prepared to stay on this drug any longer.

Started on 15 mg and up to 30 mg week after. Past 2 weeks have been on 45 mg. I was told at higher doses it would be less sedating but this hasn't happened. The worst side effect is my overwhelming feelings of anger and rage. I've never been an aggressive person but this drug makes me lose my rag at the slightest irritation.

As for helping my depression it has done absolutely nothing. Very disappointing as a recent study in the Lancet suggested that Mirt along with Lustral and Escitalopram were all highly effective. I guess it's a case of different meds suit different people. I'm going to try and get switched to escitalopram (Cipralex) although due to its cost I'll probably get the runaround.

What annoys me is when the GP says 'You need to give it (the drug) time.' From everything I've read, the current thinking seems to be that if an antidepressant has NO effect whatsoever by 4 weeks then it will not have an effect in the future regardless of increasing the dose.

I've got a medical background so have been researching like crazy on this :roll: I think one of the key problems is that GPs see the bulk of depression and the bottom line is that they are not experts in mental health. My GP for example wasn't aware that Seroxat came in lower doses than 30 mg?! That is worrying...

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  • Edited

    Been on MIRTAZAPINE just over 3 weeks. Think I have had every side effect mention.Terrible nightmares tired dopey most of day stomach cramps etc etc. I now getting angry and bad tempered usually mild mannered I am becoming frightened of how I feel. Seeing GP next week praying some good will come from appointment.

  • Posted

    I'm glad I found this thread. I've been on Mirtazapine for 7-8wks now & I'm struggling the very same as most of you. I want off of this med ASAP. 😨

  • Posted

    same boat. SO glad I found the thread, I thought I was imagining it, but the slightest little thing will set me off lately. I am usually super quiet and passive, but after two weeks of this drug at 15mg, I've started lashing out at people over basically nothing, and feeling on edge all the time. Not to mention the extreme sedative effect; I feel like a zombie. Hopefully getting off soon, seeing psychiatrist in a week or so.

  • Posted

    Your post has helped me so much to know that I wasn't alone.

    I was on it for a month, maybe less, when I went on a vacation with my mom and her friend. I pretty much ruined the vacation with my irritability and hostility.

    I've been off of it for just under 4 weeks, and it was very challenging. At 21 days, I felt completely back to my self. But it was rough, to say the least.

    I am so sorry that you have also experienced this. Thank you for sharing your experience.

  • Posted

    Hi. I've personally had depression for 4-5 years now and only recently decided to get help after getting really low and almost doing something I shouldn't have. I was started on Sertraline which worked instantly but I got really bad side effects. I was then moved on to 10mg of Citalopram which didn't work at all so was moved on to 20mg, then 30mg and no change. Finally I was moved on to 15mg Mirtazapine and it works...I'm now able to sleep. I haven't been able to get more than 2 hours a night in a good few months since starting my depression medication. There are of course the usual side effects which seem to be being able to sleep very well (I could sleep most of the day if I let myself) and my dreams are super weird, I can also remember them all day rather than forget as soon as I wake up, I feel hungry most of the time but luckily exercise as much as possible and I also feel like certain emotions have either been dimmed down or just shut off...Like I could cut contact with someone and feel nothing. I've also noticed that I can write things a lot easier, it's hard to explain but I find myself replying to comments or writing social media statuses with a lot more depth and feeling. I've also noticed myself getting mad at the most trivial things. My doctor isn't exactly the best to be honest and didn't mention a single side effect, I had to search them all myself and to be honest, I wouldn't say any of the side effects are bad because as far as I see it, my depression is no longer an issue.

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