Rash tapering off mirtazapine

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Hi I'm currently on 1.5ml mirtazapine but have come up on a rash.... Is this a known withdrawal does anyone know?! I wouldn't put anything passed this drug anymore! 

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  • Posted

    Hi, Dee Dee,

    Unfortunately, mirt binds to histamine receptors very strongly at lower doses. That is why it works for sleep at lower doses. For me, I have been proactively taking Benadryl since the start of my d/c. I experienced that with another a/d. I can only say my experience. Benadryl ALLEGEDLY causes drowsiness...i have seen none as I am taking it at night....and so not sleeping. I have HOPEFULLY bypassed the itching. Keep us posted. Stay Strong, we got this!!! XO

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    • Posted

      Dee Dee,

      I have found that avoiding hot water...shower, tub is helpful.

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    • Posted

      Hi Gretel:  As Mirtazapine has an antihistamine base, 4 some people, myself included, it causes insomnia big time as we are paradoxical 2 it.  Benadryl is also a antihistamine so that is probably why u r not sleeping.  This is also the reason I had to get off both Mirtazapine and Seroquel as they caused me 2 have major insomnia both on and off them in w/d.  I am still suffering horrendously and I am 19 weeks of Mirtazapine and 11 months off Seroquel.  These drugs get stuck in the fatty tissues and r a horror story 2 get off.  I didn't find that Mirtazapine or Seroquel helped in any way nor did Gabapentin or Zoplicone which I have been off 4 2 years now. 

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    • Posted

      Hey Barbara,

      Thanks for the info, i took my benadryl as i was reading. I am going to skip it tomorrow.

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