Recurring Hepatic Encephalopathy

Posted , 4 users are following.

Looking for advice. My father has end stage liver disease caused by alcoholic cirrhosis. He was diagnosed 5 years ago, and has gotten really bad in the last year. He suffers from a number of complications, but the most debilitating is hepatic encephalopathy. He just went back to the hospital again today for the 10th time this year after his ammonia levels had increased to the point of being unable to talk or walk or use his hands or swallow, despite having been on 35 m/l of lactulose every 2 hours for 24 hours (normal daily dose is 30 m/l 3x per day) to try and bring ammonia down at home. Same cycle as always, same progression, same symptoms. He just had liver panels and other blood work done last month after a 20 day hospital stay. No significant disease progression from that standpoint. We just cannot keep his ammonia under control, despite following doctors orders to the letter. Just keeps happening. Any advice/similar experience would be appreciated.

1 like, 3 replies

3 Replies

  • Posted

    Ask your doctor about Xifaxan. It can be used alone or with lactulose.

  • Posted

    I am dealing with something similar with my mother, but having 45ml (3 times a day) of lactulose helped with all her impaired cognitive and motor skills. Any update on your solution?

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