1. Community
  2. Skin and nails
  3. Urticarial Rash

Recurring urticaria, reaction to Ibuprofen?????

Posted , 7 users are following.

Jbridge85
Jbridge85

Hey there I am hoping someone can help me. I have had 4 episodes of hives since Jan. They have progressively gotten a bit worse. I have been to the ER, my PCP and most recently an allergist. They have ruled out autoimmune d/o through testing thank god, no celiac and I cannot pinpoint a trigger to these. I have been on steroids every bout of these. I am taking Zyrtec 2 in the am 2 in the pm, Ranitidine 150 twice a day, Singulair every night and Benadryl as needed. This round had disappeared completely by the time my steroid taper was done, as I was at work today my back started to bother me so I took 600 mg Ibuprofen and within 2.5-3 hours my face was tingling, eyes and lips swelled and the hives started on my neck. I went to the ER where I was given yet another Medrol dosing pack to take as well as my other meds. I randomly asked if I could taje Ibuprofen for the swelling and the doctor told me absolutely not, NSAIDS can exacerbate these hives and usually happens within 1-4 hours. Has anyone else EVER had this reaction. Looking back at the episodes I have had I probably had taken Ibuprofen unknowingly and hadn't mentioned this. Please tell me I am not alone. Thank you all so much.. I HATE THIS. 

0 likes, 11 replies

11 Replies

  • alicia08986
    alicia08986 Jbridge85

    Posted

    hi

    Yes the doctors are correct. I took iburofen myself and immediately the hive started again. The only thing that works for me so far is predonisolone. I have been having xolair which does not work at all. I have had utacaria and angedomenia for 2 years. Still no cause found had all the testing and still nothing apart from i produce to much histamine. Sorry to hear your suffering. Aloe vera works wonders for itching and takes the swelling of hives down almost immediately. :-)

    • Jbridge85
      Jbridge85 alicia08986

      Posted

      Thank you for your reply. These hives are insane and I am willing to try anything at this point. The doctor did say if this med regimen didn't work I would have to go the Xolair route. I will def try the aloe vera. Hoping maybe if I avoid the NSAIDS I can keeo these hives at bay. Thank you!

  • jana94738
    jana94738 Jbridge85

    Posted

    I cant take any nsaids whatsoever as they cause a terrible outbreak of hives.. or make the ones i already have that much worse . I use essential oils or australian dream cream when i have back pain and peppermint oil for a headache..  I am now taking xolair shots once a month so I only have a few hives here and there and used to have them so bad i ended up in er.. I have had these for one year and the xolair is only a bandage as they do not know why I am getting these either after 40 years without them.. I would speak to your dr about the nsaids and see what he or she has to say.. good luck this is so not fun having the hives..
  • Jobeso
    Jobeso Jbridge85

    Posted

    Sorry to read about your struggle. I am currently writing this msg in office and have a bout of an outbreak m. THhere is no medication I can avail right now but I calm myself down and try not to think about the itchiness and sensation through my body.

    I usually take montair, mildly sedative, and If it is really bad outbreaks, then I take citrizine, but that is strongly sedating.

    I know two allergens - triggers, yeast and gluten. 

    You are not alone. 

  • madeleine92139
    madeleine92139 Jbridge85

    Posted

    I got this rash 3 years ago and it lasted from January to May.  I went to 7 different doctors in five months and no one was able to help me.  I felt that it got worse with prednisone and stopped that.  A sweet Hispanic woman I worked with told me to buy the Mexican herb Epazote de Comer and brew it as a tea and drink and apply to hives for 5 days.  It was gone in two!  So now, 3 years later they are back and nothing is working.  I do take Ibruprofen so I wonder if I should stop that. The itching is awful but the worst is on your face.  Even with make-up it is hard to hide.  I HATE THIS TOO!
    • Jbridge85
      Jbridge85 madeleine92139

      Posted

      Did you stop the Ibuprofen? I think it will help. I have done a lot of research and did talk to my allergist who said 20% of people with Idiopathic Urticaria are intolerant to NSAIDS and they make it worse. No ibuprofen, Aleve... etc
    • madeleine92139
      madeleine92139 Jbridge85

      Posted

      I did stop the Ibuprofen daily but have probably had one a week for aches and pains.  I didn't notice that it made a difference in the welts. I have Urticarial Vasculitis.  My endocrinologist wanted me to go back to the dermatologist but why waste our time.  He couldn't help me before.  I have gone on a Keto diet now.  So far, no help with welts, but I've lost 20 pounds! I'm sure it is probably stress.

    • wendy62425
      wendy62425 madeleine92139

      Posted

      Hi Madeleine

      i have Chronic Urticaria and have been told not to have NSAIDS either.  Please let us know how you do on the KETO diet.  I hear you have to give it time and it's good for us.... except the losing weight part as I already have lost too much...unless it will come off my backside 😊. I also get migraines from time to time and have been told that the KETO diet will help that.  I have had the hive breakouts three times in my life....each time I think to to stress.  Each time lasting at least two years then gone for a decade.  I am now 66 and have had the Urticaria this time since July 2015 and am on 1mg Prednisone and 1 Allegra a each day to keep the hives gone

  • wendy62425
    wendy62425 Jbridge85

    Posted

    Yes.....I am unable to take NSAIDS as well due to the Urticaria.  Did not want to experience what would happen after doctor said not good for hives.  I have been on very low dose Prednisone 1mg some days 2mg if I get stressed about something as stress is one of my triggers.  I started to do 1mg Prednisone every other day....did well but then started to breakout slightly...... I may have to accept that I need to take the low dose for a very long time.  This is the only thing that keeps the hives away for me.
  • niamh94886
    niamh94886 Jbridge85

    Posted

    Yes - please look into a low salicylic diet! This means no more pain killers esp ones with codeine. You will need to change toothpaste also to one without mint or salicylates. I have even changed shampoo. I have been on this diet for 5 weeks. It should be combined with medication such as montelukast to see real results! 

    It is highly likely you have an intolerance to salicyclates and the result is Urticaria! Perhaps visit an allergy specialist who deals with sinus issues.

    Good luck!

    • Jbridge85
      Jbridge85 niamh94886

      Posted

      This is the first I have heard of this and I have been seeing an Allergist. Thank you, I’m googling Now!!
Back to top

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.