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severe back pain within an hour of taking methotrexate

Posted , 11 users are following.

donna82193
donna82193

Im on my third dose of taking methotrexate. Not noticed any change and side effects have been manageable BUT after an hour of taking it my lower back is agony. Its like im being stabbed all over. After 2 or so hrs it goes. No painkiller touches it.

Anyone else had similar reaction??

Many thanks

0 likes, 61 replies

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  • cheria
    cheria donna82193

    Posted

    Gosh, please stop taking this medication until you do some research on this..this could be greatly effecting your kidneys.. Can you tell us why you are taking this daily? This normally is taken one day a week, starting with 2 or 3 tablets..
    • donna82193
      donna82193 cheria

      Posted

      Hello.

      Sorry I take it once a week for RA. This is my third week and each time my back hurts. Its in the muscle area that runs either side of your spine. Its horrible.

  • cheria
    cheria donna82193

    Posted

    Gosh, please stop taking this medication until you do some research on this..this could be greatly effecting your kidneys.. This medication has strong warnings regarding risks with kidney failure leading to death..Can you tell us why you are taking this daily? This normally is taken one day a week, starting with 2 or 3 tablets..
    • cheria
      cheria

      Posted

      There is what's called referred pain..which sounds like is a possibility from where you've described your pain..would you say this is in your low to middle back? Have you asked your doctors nurse, or called a nurse in your local ER to get her thoughts about whether you should be seen right away? Methotrexate is associated with liver toxology and and serious co morbid complications. You may want to get a few professional opinions and your own feelings about this before taking another of these. These were poison for me and caused all over pain and cause a compromised immune system leading to infection in the body, including kidney infection, dental infections, ( loosening of teeth and infection getting into the roots and then becoming systemic, and other infections) ..
    • donna82193
      donna82193 cheria

      Posted

      This drug makes me think i'll get worse not better. Its from middle to lower back. I have osteo in spine so it may be aggravating that. Ill call rheumy nurse tomorrow. Thanku. X x
    • cheria
      cheria donna82193

      Posted

      I am wondering if you have stopped taking the methotrexate...? Side effects from this drug greatly lowers our immune system and induced pain in so many places in me....is toxic for many and symptoms like yours are listed in the medication insert guven by the pharmacist as toxic reactions to this medication.
  • Debkimly
    Debkimly donna82193

    Posted

    I have been taking methratrexate for couple of months and nothing like that.  I do drink two big glasses of water when I take it.  I am up to 20 mg and all I've noticed is hair loss.  I would call your Dr just to ease your mind.  
  • mrsmop
    mrsmop donna82193

    Posted

    Hi Donna,  I took MTX for 18 months until I could no longer tolerate the pain it caused in my hips and thighs.  I stopped taking it in February and still have pain, though it is now tolerable.

    Talk to your Consultant.  I have now spoken to mine [Dermatologist] and he is looking to put me on a different drug

    I took Co-Dydramol at night, which helped me sleep through the pain for a few hours but, as you say, nothing much helps.

    • donna82193
      donna82193 mrsmop

      Posted

      Hello

      Thanku I will speak with him. Its also making my neuropathy worse so something is not right.

    • mrsmop
      mrsmop donna82193

      Posted

      When I mentioned the pain to my Dermatologist, I also remembered that I had had pain like that, when I took Alendronic Acid.  He asked me whether I had taken Atorvastatin, which I had and I had also had to stop that because of leg pain.  The Atorvastatin was about 15 years ago, so I don't know what he was thinking about.  We are discussing it further in 3 weeks time.

       

    • donna82193
      donna82193 mrsmop

      Posted

      Let me know what he says. I know mtx can cause neurpothy so im assuming its making mine worse.

      Ive apoken with consultant and ive got to split my dose. Three on sunday then three on Wednesday. We will see what happens.

    • donna46780
      donna46780 mrsmop

      Posted

      hi there.  I have Progressive Multiple Sclerosis, and am on a low dose of oral methotraxate.  I have been on it for about 8 months and am experiencing hip and thigh pain tenderess in my rib region, and tenderness n what seems to be my kidney area all the way through to my back.  Y our post threw up a ed flag.  I'm going to call my MS specialist, but have you had any of the other problems I'm having with the metho. ?

       

  • peter_webb
    peter_webb donna82193

    Posted

    speak to your Dr or Rheumatoligist asap as it sounds like you cannot take that much medication in one go or that drug with out some sort of steroid pain killer
    • donna82193
      donna82193 peter_webb

      Posted

      Hello

      Ive spoken with my specialist and he has recommended splitting the dose. I took three last nite and will take three on Wednesday. It worked no pain.

      Fingers crossed it carries on. :-)

    • cheria
      cheria donna82193

      Posted

      Thats such great news.. Do gou also take prescribed folic acid to prevent any nausia from the depletion of this from methotrexate?
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