Should I have another prostate biopsy

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I had a prostate biopsy about 3 years ago. It''s negative. After the biopsy. I got an infection (sepsis). About 1 year ago. I got a DNA methylation. It's positive at the right apex. Another MRI after that.The MRI is negative.I just got a the PSA test a week ago. It goes up to 11. The doctor wants to do another biopsy at the apex where the DNA methylation shows positive. Should I have another biopsy. I'm scare of getting the infection like before.

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  • Posted

    Can you have the biopsy done through the middle of the groin, I can't remember what they call that area, but in those that are high risk for infection they take it that way instead of through the rectum. I don't blame you one bit for not wanting one. I am on immune suppressant for Crohn's and I would be vulnerable to sepsis. Did they give you antibiotics for the last one? If so then it would be a bad idea to have it the traditional way. They do saturation biopsies through the outside instead of going through the rectum, so it is something to ask your doctor about. If you didn't get the antibiotics for the last one, then what they do is take a swab of the rectum, culture the bacteria that is present and test antibiotics that they commonly use on the sample to make sure it will be able to prevent sepsis. If it doesn't work they will try another antibiotic until either they find one that works or if they don't then they don't take the sample through the rectum they will go through the perineum, that is what it is called. They can do it that way instead and there is practically no chance of sepsis when they do it that way. It costs more because they do it in the hospital and you usually are put out for it. That is what I would choose. I wish you luck and hope that everything goes well.

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  • Posted

    Thanks for your inputs. The doctor told me this time He would do it in the hospital under antibiotic. He didn't tell me from where. Even in the hospital but I still worry very much about the infection.

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    • Posted

      Make sure you ask him, it can be done through the Perineum and it is the safest way. From what I read there has been few to none having sepsis from that type of biopsy. It is what I would do. I wish you luck and hope it all works out.
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  • Posted

    I have resisted biopsy because it hurts and infection is not uncommon.  I opted for a high definition MRI instead. Showed clear.  My PSA is measured half-yearly.  It showed 6.2 in February. So sit on my hands for moment
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