1. Community
  2. Bones, joints and muscles
  3. Methotrexate

Should I stop taking MX??

Posted , 5 users are following.

john81314
john81314

I have been on MX for 6 months started with 10 now on 25 mg 

For Inflammatory arthritis pain joint swelling got worse despite Increased dosage is taking MX making my  

condition worse. ?

0 likes, 8 replies

8 Replies

  • mrsmop
    mrsmop john81314

    Posted

    I have been taking it for 7 months and have been on 10mgs the whole time.  [I am on it for Cicatricial Pemphigoid] I am being weaned off Prednisolone at the moment and am gradually feeling worse and worse.  My mouth [which is the worst part at the moment] is getting more and more sore and, I don't know about you John but I feel pretty much on my own here!

    So in answer to your question,  I haven't a clue, sorry.

    • joanne27239
      joanne27239 mrsmop

      Posted

      I'm on 25mg for phoriasis. I've been taking it for nearly 5 years. 

      I use to suffer awful with a sore mouth. Full of ulcers. Till I had a shot of Sambuka. Boy did it sting but it soon cleared it up. 

      When I asked about it I was told it was the liquorish which is really good for sore mouths. So I often just buy liquorish and it has kept the ulcers away. Only get a flare op now and again. 

  • steve2407
    steve2407 john81314

    Posted

    Hard to imagine that MTX is making your Arthritis worse given how it is designed to work, but is this all you are taking? In my experience it took a combination of MTX, Leflunomide and Arcoxia to get anywhere near containing my Psoriatic Arthritis!
    • john81314
      john81314 steve2407

      Posted

      Hi Steve I also take acoxia (couldn't live without) and Hydroxy chloroquine for lupus (which was drug induced) hence my hesitancy with MTX how long did it take taking MTX before you felt better? ?
    • steve2407
      steve2407 john81314

      Posted

      Hi John, it's been several years that I've been on MTX but I think it became effective for me only once the dose was raised to 22.5 so probably 6 months or so. From the posts I've read on this and other sites I totally respect the fact that everyone's experiences of these drugs differ quite widely, so I hope your Rheumatologist, eventually gets the doses right for you.
  • linda31779
    linda31779 john81314

    Posted

    hi john,i too am suffering from the same, iv been on mtx for almost two years, and have been telling the doctor its not working,i swapped to methoject three months ago, and had a nuclear bone scan two months ago rvealing that i have no inflammation but further deteriation. so i guess this means that the mtx is finally working but cos of the delay it caused more damage. im taking 20mg methoject, folic acic and hydroxychloroquine. hop this helps.
    • john81314
      john81314 linda31779

      Posted

      Thanks Linda sounds if I should persevere just as a matter of interest how old are you I'm 66
  • linda31779
    linda31779 john81314

    Posted

    hi john, im 41, to be honest i dont really feel any better, but i got to have both knees replaced so maybe when im not in so much pain things will start to look up =)
Back to top

Report or request deletion

Thanks for your help!

We want the community to be a useful resource for our users but it is important to remember that the community are not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in respect of any healthcare matters. Always speak to your doctor before acting and in cases of emergency seek appropriate medical assistance immediately. Use of the community is subject to our Terms of Use and Privacy Policy and steps will be taken to remove posts identified as being in breach of those terms.