Should I take Alendronic Acid?
Posted , 3 users are following.
I suffer from Polymialgia R and have been for a year now. My doctor put me on Prednisolone steroids and Alendronic Acid, but, I heard such negative things about the latter that I decided to give them a miss as I was only expecting to be taking the Preds. for a year, and thought that a high intake of calcium and vitamin D would do the business.
The doctor now tells me I will be on steroids for at least another year and possibly a lot longer.
Should I start taking Alendronic Acid or is there a better option, or at least one with less drastic side effects? I'm a sixty five year old male who has several Auto Immune Problems who until the onset of PMR considered myself fairly actve.
0 likes, 9 replies
EileenH steve_1
Posted
You should request a dexascan to assess your bone density status. If it is fine then you can continue as you are. If you are already osteoporitic or borderline, then make your considerations on that basis.
Taken carefully in accordance with the instructions AA is found by many patients to be OK. For some years it was touted as the miracle to avoid every fractured hip in the elderly - more recently it has been realised that, while it is good, it is not THAT good. It has side effects (like every drug) and some of them mean it is better not to take it continuously for ever, it is recommended it not be taken for more than 5 years without a break.
First of all, ask for a dexascan. If your GP is difficult about it, it is possible to get them done privately and they aren't desperately expensive in the great scheme of things.
If you are shown to be immediately in need of "bone protection" medication then discuss it. There are other options. There are other bisphosphonates with differing profiles and there are other substances - but to be considered for them you have to have "failed" the first line things (to use medical parlance) or there must be a good reason for you not being put on them (preexisting gastric problems such as reflux etc) or allergy. All have some side effects.
beulah steve_1
Posted
PS They are trying to ban this drug in the States.
EileenH beulah
Posted
The difference between PAD and PMR is that PMR would respond dramatically to a moderate dose of pred (15mg). Any patient who does not respond like that - and by dramatic I mean a 70% improvement in symptoms generally within 24-48 hours - MUST be investigated for other possibilities, including PAD.
beulah EileenH
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EileenH beulah
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There are no conclusive tests for PMR - as I'm sure you are aware - but yes, you are right, it doesn't sound greatly like PMR if it took 30mg. That is part of the reason for only using 15-20mg to start: only PMR responds so typically to that, other things respond to higher doses too. My ESR/CRP were also low, ESR never above 7, but I responded in 6 hours to pred! The GPs were definitely at fault if they allowed him to continue with claudication - since that is a strong sign of GCA or at least LVV (large vessel vasculitis) and if the pred isn't improving it then it need to be referred to a vascular surgeon for assessment (my husband ran a diagnostic vascular lab so I gathered a fair bit about that, even working there for a while).
Have they considered his adrenal function? Done a synacthen test? That would fit with the reaction if they try to take the pred away altogether.
beulah EileenH
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EileenH beulah
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beulah steve_1
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EileenH beulah
Posted