Side effects- Nalmefene ( Selincro ) v Naltrexone.

Posted , 9 users are following.

Okay an update.  Most people who have been on this forum a while will know my story. If you don't well it is all there in varies threads if you want to read it.

Quick back track.  Sucessfull 6 months on Nalmefene ( Selincro ) but the more successful the less I required the drug and the side effects increased again when I did need to take a tablet. Issues getting prescribed Naltrexone ( perported to have less issues with side effects ) so for that reason and pain relief problems I discontinued Nalmefene ( Selincro ) . I drank without protection and for the last two months I have continued to do well. Units consumed per week around the new UK government recommendation of 14 units. ( less than that many a week ) However, I am well aware this can change and I will return to the way I was before.

I am not a person who would buy drugs online, however, after advise and a recommended source of a reliable company I obtained Naltrexone. ( This is while I am pursuing ongoing avenues to have the drug prescribed. 

I have only taken it twice so far. The side effects were no where near as dreadful as Nalmefene ( Selincro ) and as I later realised that I had started on the full dose of 50 mgs instead of 25mgs to begin with this was good news. The second dose had minimal side effects. I would just say a slight 'strange ' sensation hard to describe but not all worrying.  On Nalmefene I felt ill, cold sweats, nausia, muscular cramps that made me feel like I was having cardia discomfort and later travelled through the stomach and guts. Also this feeling around my nose , throat and eyes which is hard to explain.   

So in short Nalrexone is far less severe as far as side effects are concerned . It does the same job and it is a shame that the licensing issue is so complicated and unlikely to be resolved . I think more people would benefit from this is prescribed on the NHS as Selincro is now where so many people give up due to the initial side effects. 

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  • Posted

    I'm lucky that I don't get side effects from the nalmefene but I'm really glad you managed to get the naltrexone. Do you intend to take it for the rest of your life (when drinking)? Or do you feel that having had a period of drinking without protection that you would be OK in the future?

    Just wondering....

    I'm getting the nalmefene on prescription but I think it's only going to be for 1 year. At the moment I'm going to order every month to the day and hopefully the amount of tablets I can stockpile from my days off will see me through a 2nd year...

    • Posted

      Hi Foreverfuzzy, that is a very good question and one I am playing with in my mind. I now have the Naltrexone and think I will be okay with these. I have, however ,to decide whether or not to pursue a pathway I have exployed to have them prescribed via a specialist ( privately ) and then my GP to following up. I am tempted just to see how I go as I am doing really well. Then have the Naltrexone as a back up. 

      I will be making that decision soon.  If I think I will need to take them on a regular basis I will have to get them prescribed as it isn't a cheap buy.

      BTW have you been told that you will only get a prescription for a year or is that the policy in your area. Nice guidance states you can be prescribed them after a year with caution. I believe that is because the trials in Scotland were only for a year. 

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