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Side effects of mtx

Posted , 4 users are following.

susan_03245
susan_03245

hi, I've been taking mtx for 5 weeks and suffering from 3/4 days of side effects that seem to get worse every week just wondered if anyone else has experienced feeling sick, blurred vision, tinnitus and justa General feeling of pressure in my head . 

 

0 likes, 11 replies

11 Replies

  • constance.de
    constance.de susan_03245

    Posted

    Yes, I did!  Twice!  Rheumy always tried to get me on to MTX, then later, Sulfasalasine.  Both made me as sick as a pig.  Really tried, as they say it takes 3 months for it to start working.  Had to give it up though, I was losing weight and felt terrible. I'd rather suffer with the PMR and Pred.  At least I know where I am with those.

    Good luck!  Regards fr C.💐

  • bob_2020
    bob_2020 susan_03245

    Posted

    I started mtx tablets last september 20mg and never had any side effects at all on them was put on to injections then i started having side effects will be of mtx 3 weeks tmorro see rheumy tuesday coming so prob go back on to tablet form but feeling sick is common susan taking mtx wot dosage are you taking
  • C2Anna
    C2Anna susan_03245

    Posted

    Yes, this medication is a chemo drug that depletes our body of not only the bad cells but the good ones also..which lowers our immune system, inducing other conditions and diseases. Many contract polyarthritis, me for one, with my health devlining in many other ways. It induced much dental infection as well, which spread systemically causing other serious side effects. I went off from this after about 4 months, and my doctor is now attempting to get me back on this, with my current high inflammation markers. I am taking plaquinil as i dont respind well to biologics. So much more research needs to be done for this chronic RA condition, and i feel stronglt, taking into consideration magnesium and the bodys inability to absorb this and other needed nutrients associated with proper absorption, over long term.
  • gemma83759
    gemma83759 susan_03245

    Posted

    Hi Susan I took mtx in Tablet form for a year But eventually was taken off tabs cos of the nausea and being physically sick. Then injected it myself for 6 months. I, after consulting with the rheumatologist stopped it. Everyone is different but iv didn't like taking it and it certainly didn't agree with me and did nothing to ease my symptoms. I lost a lot of weight ,wad overwhelmingly tired constantly and had recurring sinus and chest infections. The general feeling of unwellness was too much. Hope it works for you and your symptoms get better soon.
    • susan_03245
      susan_03245 gemma83759

      Posted

      Hi Gemma sounds like you gave the mtx a good go. I've only been on it for 5 weeks and I've had enough already got my follow up appointment tomorrow so I'm thinking of asking to go onto a lower dose and see how that goes, I'm on 6 tablets at the moment. Are you taking ant medication now? 
    • gemma83759
      gemma83759 susan_03245

      Posted

      Hi it took me about 6 months to gradually build up to 6 tabs a day. I took one a day for a week or two them two etc etc. Got to bout 4 and was stuck there for a few weeks the 5 th one seemed to trip the nausea etc .I'm on sulfazalazine and I've just started leflunomide. Sure if u go down to a slightly lower dose of mtx and build back up the side effects night not be so bad .Good luck.
    • C2Anna
      C2Anna gemma83759

      Posted

      Hi, i have been following this posting, and am wonfering if you are mistaken about building up to 6 tablets a DAY as you have written above. The dose of this chemo drug would be 6 tablets a WEEK. Please let us know if you are mistaken!!!!!
    • gemma83759
      gemma83759 susan_03245

      Posted

      As C2Anna pointed out, I meant 6 per week. Got confused I'm taking sulfazalazine and leflunomide daily I forgot methotrexate was a weekly dose. Sorry for the confusion Susan. Gemma :-)
    • susan_03245
      susan_03245 gemma83759

      Posted

      RA nurse has taken me off the mtx today because  of the side effects I've had but she's  going to try me on sulfasalazine in September so fingers crossed it works with little or no side effects. 

       

  • BrainScribbles
    BrainScribbles susan_03245

    Posted

    I have been taking meth for about the same amount of time.  No side affects at first, but now some tummy trouble and my hair is shedding more (more noticable on the floor than my head).  I had tinnitus before starting these methotrexate and sulfasalazine.  Overall, I feel better as the RA symptoms have improved.
  • bob_2020
    bob_2020 susan_03245

    Posted

    I was seeing nurse today as well and starting on Certolizumab Pegol had a talk today about this drug and its side effects and like starting Mtx a year ago now i and a little weary but willing to try anything to help as my RA is spreading rapidly over my body....
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