simvastatin

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I STARTED TAKING SIMVASTATIN 20 MG. ABOUT TEN YEARS AGO WHEN I WAS DIAGNOSED WITH ANGINA .I WAS ALRIGHT TO START WITH BIT ISTARTED TO GET HORENDOUS CRAMP IN MY LEGS AFTER ABOUT 3 YEARS AND GRADUALLY GETTING WORSE .MY ARMS STARTED TO SWELL UP AND MY MUSCLES WERE LIKE CONCRETE I COULD HARDLY MOVE .IWENT TO THE GP SHE PRESCRIBED PARACETOMOL FOR THE PAIN .WHAT A JOKE .AFTER 3 VISITS TO THE GP I WAS SENT TO THE HOSPITAL FOR TESTS I WAS WIRED UP TO A MACHINE WITH ELECTRIC CURRENT ATTACHED TO MY FINGERS AND GIVEN JOLTS OF ELECTRICITY TO SEE IF MY MUSCLES WOULD REACT IT WAS SO BARBARIC I COULD NOT BEILIVE THEY WOULD DO THAT IN THIS DAY AND AGE THEY SAID THEY COULD NOT FIND ANYTHING WRONG WITH MY MUSCLES I AM STILL IN PAIN NOW ALTHOUGH I AM OFF SIMVASTATIN NOW ISTILL HAVE LUMPS AND BUMPS IN MY ARMS AND LEGS AND STILL SUFFER FROM MUSCLE SPASMS I VISTED MY GP YESTERDAY AND TOLD HIM ABOUT THE PROBLEMS I HAVE HAD WITH SIMVASTATIN AND HE TOLD ME ITWOULD NOT BE THT DRUG THAT WOULD BE CAUSING MY ACHES AND PAINS I THINK HE SHOULD TRY SIMVASTATIN FOR AWHILE AND THEN TELL ME ITS NOT THAT

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11 Replies

  • Posted

    Tried to reply several times, but this site is not very user friendly.

    Aged 65. Heart attack 12 years ago. On statins since 1985. Over the years have experienced muscle pain and cramps. Prescribed Allopurinol for gout (which I did not have and Voltarol which simply masked the symptoms).

    After quite some time of pain demanded a CK check which had not been included as part of the normal statin LFT check. Result was a reading of 13609Ui. Normal is about 500Ui. Doctor took me off statins. Two months down the line my CK is 7805Ui. Symptoms reduced by half (muscle pain, myopathy, inability to climb inclines, liftt legs etc).

    My advice. Don't stop taking statins without Doctors advice. Make sure your your GP is monitoring your CK levels as well as your LFTs if you are suffering muscle problems. Mine wasn't, until I insisted.

  • Posted

    Hey there!

    PLEASE do some research on co-enzyme Q10. As a diabetic, we are often prescribed statins to control cholesterol. Proven research shows that long term use of statins causes muscular spasms and, worst case scenario, these can affect your largest muscle - the heart. This is because they affect the liver's production of Q10, a co-enzyme responsible for many metabolic functions. Q10 is made by the liver but the liver produces less and less over time. By the age of 40 there is a noticeable decline in it's production. By taking statins you accellerate this decline, thus causing the classic muscular spasms, cramps, pains etc.

    Although diabetic I have elected to treat my cholesterol problem with plant sterols and other herbal remedies, supplements and foods. I would never take statins unless I took Q10 with them. My diabetic brother takes Q10 and statins. Me, just the Q10 as I'm over 40.

    My advice is to research Q10 and see if it sounds like a side-affect of the statins that's causing your ailments, then give Q10 a go. It could be that simple.

  • Posted

    Hi can anyone help im a little confused about taking Simvastatin, a few years ago I had an heart attack and I was prescribed Simvastatin with all other different tablets including heart an tablet ,I read on one site that you shouldn't take Simvastatin if you have muscular pain ,well I have suffered with Osteo Arthritis for 30 years with just about every muscle in my body and Iv learned to live with the pain and live on pain tablets the quacks prescribed that are useless after taking Simvastatin for a few years my Arthritis as got worse to the extent I can hardly walk and have to wear a big leg brace the hospital fit to help me falling all the time I look like flipping Robo Cop.I am also losing a lot of weight although I eat well and have a good appetite I have had test for cancer and they came back negative so is the Simvastatin the problem thank you for any suggestions.
  • Posted

    Was put on a high dose of Prednisolone plus Methotrexate. CK now below 1000ui and am starting to feel

    much better. Prednisolone now at 20 mg per day and Methotrexate at 7 tablets a week.

    I have Statin Induced Myositis. Diagnosis proved by way of a muscle biopsy.

  • Posted

    Prednisolone now down to 3mg a day. Methotrexate up to 8 x 205mg a week. CK reading down from an original 13609ui to 350ui. Should be 150ui.

    Feeling so much better, but any form of exercise brings back the aching muscle pain. Also have considerable muscle wastage.

    Reducing Prednisolone by 1mg each month. Methotrexate? Who knows...

  • Posted

    That should read Methotrexate up to 8 x 2.5mg a week!
  • Posted

    Hello everybody.... I have just come across this forum about SIMVASTATIN which I now considered to be one of the most dangerous drugs being pushed by big Pharma at the moment. 

    I was put on it 18 months ago and within six months was reduced by muscle wastage, painful joints, cramps and vast generalised weakness... from a healthy 70+ year-old who could walk 3 miles a day in an hour  before breakfast with my dogs,  to somebody who felt like 90+ and could, on a good day, only manage to walk  about 300 yards.... with the aid of two walking sticks.

    Sadly the effect has been progressive despite discontinuing the simvastatin and indeed I have now been diagnosed with PPFG .... Which is now an apparently recognised syndrome in its own right ... And which stands for Primary Progressive Freezing of Gait.   This  is an idiopathic, progressive and irreversible syndrome.

    It appears to be - because of the inability to move one's feet -  to the uninitiated like Parkinson disease but is NOT.  One almost wishes that it was Parkinsons as at least there would be something you could do/take for it. 

    I have been tried on a couple of the Parkinson's drugs - totally empirically - and the fact that they had no effect whatsoever - is apparently diagnostic of the fact that it is pure PPFG.

    Many of the physicians that I have seen in the course of the past year or so ,of course do not believe/or do not want to believe that this is a result of the statins.... Luckily for me some of them do  - and have warned me that I will be in a wheelchair within a couple of years at best.

    As I do not believe in medical coincidences -  and I know that symptoms started when I was on the statins, I well believe - that once our GPs and medical professionals are properly informed - and not trysted by big Pharma etc into believing that statins are the panacea to all ills .... and their blinkers are off - those of us who have suffered agonies with these horrendous drugs will be believed.

    In the meantime, as perhaps 90% of patients who are on this drug appear to be coping with it well enough  or are too afraid to remonstrate with their physicians - the financial rewards for these pharmaceutical companies are of course more important than the 10% approximately of us who are suffering.

    I just hope that in years to come statins do not turn out to be a horror story similar to that of thalidomide.  I may not be around to see it.

     

    • Posted

      Hi,

      Your symptoms sound very like mine!

      I have 'statin induced myositis'.  Diagnosed after having numerous CK checks and a muscle biopsy.  

      Have you had these checks?  If not, I really do suggest that you ask for them as your condition may well be treatable using steroids  (Prednisolone) and methotrexate.  I could hardly walk 2 years ago and can now get around the shops etc, although I will probably never walk 'for fun' again.

      I am still In pain and take codeine when things get bad.  I am seeing my Doctor next week to discuss long term pain relief.  I met someone the other day who had the same problem and she had been prescribed morphine patches.  I doubt if my Doctor will run with that...it's all a bit of a lottery!!

       

    • Posted

      Hello there Buzzard... Sorry to hear that you have been similarly afflicted.

      I am actually due to be seen by a rheumatologist in early June this year... Our waiting lists in Scotland are horrendous and anything under 2 1/2 months is regarded as "normal" 

      I am not terribly hopeful of much help however as I do know that my creatin and ESR are entirely normal.... as are all the rest of my blood tests scans etc. 

      Pain is not my problem really - I have a very high threshold.  My lack of mobility however is... and at times is extreme.  eg at times it can take me half an hour to reach the kitchen from my bedroom - a distance of 30 feet at most.

      Because of a concomitant back problem - to which most X-nurses are prone... I was seen initially by an orthopaedic surgeon who kindly injected my spine   - with great effect.  However at that point he recognised the fact that this could be the result of my statin therapy.... despite the fact that I had discontinued it some months before.  As he said then - statins side-effects are frequently irreversible and progressive - even following short courses of them and their subsequent discontinuation.

      If you care to have a look at the website of Spacedoc.com   you will find a lot of information about the side-effects of statins.... And a lot more besides which I have been following closely

      My surgeon apparently has dealt with many patients who have peripheral neuropathy as a direct result of statins. Indeed I have two very good friends who have advanced peripheral neuropathy - and whose neurologists have now recognised the fact that their problems date from their being on statins therapy - and have been caused by same.

      So he kindly referred me to a neurologist - who tried to tell me that I had obviously had a stroke. When I remonstrated - he became quite frosty - and I walked out!   I then insisted that I be seen at the stroke unit - where of course they  proved unequivocally by various scans that I had never had a stroke.... And I requested that the report was sent to that neurologist! 

      I am now under the care of a Consultant Research Neurologist who specialises in gait problems.  However he admits that there is no current medication that he can offer now - as the two drugs that I was tried on proved totally useless

      I am happy to hear of your improvement however Buzzard - and indeed I had heard of the use of prednisolone/cortisone.... But so far nobody has offered that to me... I shall of course make enquiries forthwith.... Never being backward at coming forward - my GP will vouch for that!!!!!

      Lest my problem had become an idée fixe ... I even involved a hypnotherapist - an NHS grandee I hasten to add - whose help is often invoked by GPs etc....LOL 

      He quickly reassured me it was not all in the mind...... but admitted that he could do little for me physically - however he has taught me to accept the situation -  dare I say it - with a reasonable degree of equanimity!

      Otherwise I can't imagine what life would have been like -as the frustration level increases day on day.

    • Posted

      Thanks for your long email, Alzheimer! 

      I live in the SW of England.  I see my rheumatologist every 6 months.  He, at least, has got my CK down to nearly normal.  Just the muscle pain to crack now!  I will check out the link you recommended!

      many thanks

  • Posted

    search on simvastatin, "the primary uses of simvastatin are for the treatment of

    dyslipidemia & prevention of card.,disease, it is recommendedto be used ONLY after

    other measures such as diet, excercise & weight reduction have NOT improved

    cholesterol levels sufficiently, my Doc never gave the option of trying these measures, straight onto 40mg two yrs ago, after reading this forum I stopped

    taking these ten days ago after severe cramp in legs, in a recent one wk holiday I needed a taxi twice a day to take me just 500yds to town centre,

     but what has surprised me is the severe pains in my feet (plantia fascia) have subsided and for the first time

    in twelve months I have been able to walk in comfort without insoles, would be

    interested in other guests who suffer from PF, I told my Doc who said stay off

    for four wks and then take statins again to establish cramp/feet pain returning

    the cost to NHS ( correct me if I'm wrong)  is just £1.50 month, pp which seems the reason for pushing statins, but are there more than 1% suffering with side effects

    FDA est, 60 per 1000 suffer on 80mg tablets

    according to Bloomberg new rules will put 33ml in line for statin therapy, twice the no covered by present guidlinnes, your views please

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