skin problems on prednisone? Am I infection prone?

Posted , 9 users are following.

Diagnosed with GCA and PMR in August, 2017.   I have had two or three episodes of skin rashes, mainly near my rectum.  The skin surrounding the rectum gets very pink and sometimes painful.  I have never had rashes in this area before starting on Prednisone.  I've been using  Mupirocin ointment to control it.

   What's interesting is that I have also had scalp tenderness and sores twice now, where if I itch it too much, the sores bleed.   My dermatologist diagnosed the scalp sores as a staph infection and instructed me to use the mupirocin on my scalp, which I do, but it is very greasy, so I have to be judicious about it if I want to leave the house.   The scalp also feels very tender to the touch or if I brush my hair. 

   Has anyone else here experienced scalp sores/tenderness or other rashes since starting on Prednisone?   I know that Pred can make one susceptible to infections, but I just am not sure that this is very common?  

   These rashes are not allergy related and no, I have not switched detergents or used any new shampoo.   I am interested to know how many others have had these problems.

thanks,

Pam

1 like, 24 replies

24 Replies

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  • Posted

    If your rash is due to fungus/yeast infection and not something else the following has helped me, with advice and tips from my doctor. We are probably not allowed to give brand names but you can also buy a cream containing hydrocortisone over the counter, and if the condition doesn’t clear talk to your doctor about a cream which includes a low dose anti biotic. You apply it locally 3 times a day and it can be combined with a pessary. Wear skirts when you can, cotton underwear, avoid those wet wipes when you go to the loo, reduce sugar and acid creating foods, just use water to clean the tender area and avoid soap. Hope this helps and that this rash is at least a simpler symptom which can be helped. It’s uncomfortable and lowering. 
  • Posted

    Just FYI, over the counter hydrocortisone cream did not work for me, nor did the candida cream. Just not a strong enough anti-fungal agent I guess. The prescription I get here in Canada is a 1:1 compound of hydrocortisone and nystatin..
  • Posted

    Pam, I worry about self diagnosis with these things and self treatment. Some antifungals are contraindicated with pred. 

    My father had an eczema type rash for many years on his legs. He tried all sorts of otc creams but the rash started to spread. I finally took him to a skin specialist. His diagnosis cutaneous T cell lymphoma. The treatment: take a certain medication and go stand in a light box. This put him into remission and he lived to 81.

  • Posted

    Another thought: an allergy to a cream or other products can occur at any time despite years of previous successful use. In my case before pred I had a rash on my chest for which a steroid cream was prescribed. The rash got worse. I eventually went for skin testing: the verdict: allergy to propylene glycol a common stabilizer in many meds and cosmetics. I am also allergic to the neosporin in many otc antibiotic preparations. All this born out in skin testing.
    • Posted

      And not only may you develop an allergy to an existing ingredient but sometimes the formula is changed, and who reads the fine print every time, especially for something which has been fine before?
  • Posted

    Responding to the little conversation here about hydrocortisone ointments.  I've had experience of this, and I have to say it gave me a dress rehearsal for tapering prednisone.  Used to get patchy, itchy red skin, especially on my hands, and cortisone would be prescribed by the doctor, but the condition would always come back after I discontinued the medication.  Eventually I learned there was a rebound reaction.  I started first of all to reduce the power of the medication by switching to the otc version.  Then I spent quite a long time looking for another cream or lotioin which would help me.  I tried everything, from vaseline to olive oil to the most expensive items in the pharmacy.  in the end I was by chance given a bottle of food grade h*** oil and this made all the difference.  Over time I no longer needed the hydrocortisone, and using this oil, and also a product from the pharmacy which contains shea butter, I've been fine.  The apparent cure (although I think it's like PMR and is really always there waiting to flare up) was long before PMR and pred.

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