Sleep problems.
Posted , 8 users are following.
I have been taking 8.5 mg of predisone at about 5:00 pm. I am just wondering what is the best time to take prednisone to get the best nights sleep. I have been waking up after about 5 hours of sleep & have difficulty getting back to sleep.
Thanks.
0 likes, 17 replies
tavidu mary68968
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mary68968 tavidu
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I will try taking in the morning. If my sleep patterns continue this way I may as well get a night job. :-)
EileenH mary68968
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In PMR the recommended time to take your pred is all as one dose, as early in the morning as possible with some food. Studies have shown the absolutely best time to avoid morning stiffness is to take ordinary white pred tablets at 2am, which allows the peak blood level to occur at about 4am before the cytokines that cause the inflammation are released. If you were using enteric coated pills then you would take them a few hours earlier to achieve a similar effect.
I'd think that 5pm was perhaps about the worst time - your peak blood level will be before midnight and the body reacts to cortisol naturally to prepare for the day ahead so that is why you wake and can't get back to sleep.
mary68968 EileenH
Posted
Why 5pm? I have no idea. I tend to go to bed early so I guess I just kept stepping the pill time up. When first taking pred the side effects bothered me when taking it the morning so that's why I took it a night. I will go back to am again & hope for a sounder sleep.
Thanks
EileenH mary68968
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JandaPea EileenH
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And that of course is what we are all searching for, 'what works best for the individual'.
As an aside 2 1/2 mg of pred. come in enteric gastro resistant tablets, I have ditched these and when I want 1/2 mg. pred I use a pill cutter on either the 5 to make the 2 1/2 or 1 to make the 1/2mg pred, I am on a reduction program, SLOWLY. SLOWLY.
Cheers.
Janda
tina-uk_cwall JandaPea
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mary68968 JandaPea
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EileenH mary68968
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mary68968 EileenH
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tavidu mary68968
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mary68968 tavidu
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Back to regular programming.
tavidu mary68968
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mary68968 tavidu
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tavidu mary68968
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