Sleepiness on Mirtazapine

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I have been on 30mg of Mirt for just over a week. The first week was not too bad and I felt a bit groggy first thing every morning and then I was more alert, however the last two days I have been felling groggy and sleepy all day really (I used to feel like this for a week on 15mg before I upped to 30mg). Will it pass or or moving up to 45mg would reduce the feeling of groggines and sleepiness? I feel it is takjng me out of deep depression but I am nowhere near being my old self...

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11 Replies

  • Posted

    I'm on 45mg each night. No not gained weight, I've lost weight. Yes taking for depression along with venlafaxine.

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    • Posted

      Wow, that’s great! I am doing everything not to put weight on this time... I was on Mirt 6 years ago (on 45) and I was feeling extremely hungry and ate what I wanted. I put 2 stone then in 5 months. This time I am extremely careful

      and exercising to help to boost my mood and energy levels. How long would you say it took for Mirtazapine to work and improve your mood? 

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    • Posted

      All honesty it took adding venlafaxine to my mirtazapine to notice improvement in my mood... mirtazapine improved my sleep and my appetite.
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    • Posted

      I saw my GP today and she said she would not add anything or change. Have to stick to 30mg  for longer to see whether it helps.... I am hoping it helps, it did last time bit it took 2 months nearly. Did your Go prescribe you the combo? Or do you live outside of the UK?
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  • Posted

    Hi,i take 15mg every night and have been on them for a year and still find it hard waking in the morning but im fine after ive been up 20-30 mins.
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  • Posted

    Hi, have you increased dose by yourself or under the direction of your doctor? It tends to be feeling more sleepy on the lower dose.  It can take a couple of weeks for things to even out when starting this medication.  I felt better after a couple of days on 15mg and have not had to raise my.  Just go with it and you will feel better soon.  After a month or so I was back to being me.  Hopefully you will be the same as most people on this have good results, Good luck.
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    • Posted

      I hope this is just a phase feeling groggy and slower mentally. I can’t remember feeling like this on 45mg. I used to be only on 45mg in the past so can’t compare. I have been on Mirt for 3 weeks altogether but when you  increase the dose it probably take some time for the body to adjust.
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