Something I need to share with you all

Posted , 5 users are following.

This I something I found out today from an American physician.

The idea that depression results from a chemical imbalance in the brain theory has been around for more than 50 years. This is based on a theory that depression results from a deficiency of serotonin a chemical substance that nerves use to send signals to each other. There is no convincing evidence that depression results from any kind if of chemical imbalance in fact the psychological and biological causes of depression are still completely unknown. There is probably a genetic contribution depression as well as anxiety just as there is a genetic contribution to how athletic we are. Some people are probably born to be more outgoing or painfully shy but we simply don't know how strong the genetic contributions might be or how this works. Infact we still don't know to what degree depression and anxiety result from hardware problems in the brain such as abnormality with brain tissue structure or metabolism vs software problems involving learning and neural circuitry. Drug company's encourage doctors to tell patients that depression results from a chemical imbalance in the brain in order to sell antidepressants. So if a doctor tells you that you have a chemical imbalance it seems logical to conclude that you need drugs to correct this imbalance but this is more of a matter of marketing science and to me is ethically questionable to tell a patient he or she has a chemical imbalance in the brain. I am a physician and been trained not to tell patients things that cannot be validated with lab test for chemical imbalance in the brain, there is no convincing basic research that has confirmed this theory either. I began my psychiatric career doing full time brain research at the university of Pennsylvania school of medicine I focused on the chemical imbalance theory and won awards for my research unit in the Philadelphia va hostpital, we gave depressed veterans massive daily doses of L tryptophan an essential amino acid that the brain uses to manufacture serotonin. The massive increase in serotonin levels had no effect whatsoever on the depression levels in our patients. My colleagues and I published this finding in the top psychiatric journal but it went largely unnoticed until recent years and is now being quoted quite a lot.

1 like, 24 replies

24 Replies

  • Posted

    well done. what will be your next step     ////, howard in the uk.
    • Posted

      Well it seems its still not fully understood. From all the research I have done over the years there are still no real answers as to why we suffer this illness. All I have learnt is that antidepressants don't work and we have to find other ways to deal with this condition.
    • Posted

      We have to keep tryimg mike,,,,, well , you  rather than me , as i am now retired...one of my old colleagues. dr. chris pomfrett, still spending years looking into prion disease.....if you come up with new findings, i will be one of the first to applaud, yours, howard, staffs., uk
  • Posted

    I heard something about germs or infection causing emo problems. However I am watching a fascinating video on Ted, check out Depression as a Symptom of Civilization. He lists a bunch of ways to combat depression, basically saying we are not living as nature intended:

    get exercise, get sunlight, get omega 3 fats; healthy sleep; activity rather than ruminating; and be socially connected. Basically as our anscestors were for thousands and thousands of years.

    • Posted

      This would be a REAL "lifestyle change" :P
  • Posted

    Michael

    So will ssri work for me I have anxiety, depression, panic and agriphobia aswell as dissociative disorder. Ive never really taken meds but I think I really need to now I feel very detached from myself and surroundings.

  • Posted

    Michael, having read what you say about chemical imbalance in the brain being only a theory and serotonin making no difference to depression please tell me, why then do antidepressants appear to work?
    • Posted

      Hi blu

      I don't know the answer but please note that what I wrote was from a psychiatrist and was not my words. I'm happy to hear that the ADs work for you. I wasn't so lucky as was on them for 32 years and they never worked for me, they did seem to work in the acute phase but after that they didn't do a thing for me all that happened was that I suffered very bad side effects so I won't take them anymore and feel much better now I'm off them. Also we have to bear in mind that what David burns MD was saying is just theory and not fact. I thought it was an interesting artical so that's why I posted on this forum

    • Posted

      Sorry, misunderstanding.... I thought when you wrote "This I something I found out today from an American physician." that you were a physician too!! Ha!
    • Posted

      We could start a new section....

      Ask Dr Mike

    • Posted

      "Dear Dr. Mike:

      I have this dog that...."

    • Posted

      That is so funny. Ps wish I was a doctor then I wouldn't be so skint lol x
    • Posted

      Well if she has another one then tell her not to worry as that's just normal as that are known as tits
    • Posted

      It's good to have a laugh for once x
    • Posted

      It's good to have a laugh like this instead of talking about being depressed x
    • Posted

      Hi Sarah

      Hope your ok today. I'm having a real bad day my depression has gone from bad to worse, nothing horrible has happened I just woke up this morning feel so awful. I kept waking in the night as was having bad nightmare that I was in a mental hospital and doctors had me tied to a bed and were injecting me with drugs it was so vivid and woke up shaking in fear and just been feeling so ill all day it feels like I'm losing my battle and moving backwards not forwards and after them dreams I'm worried that it was a glimps of the future

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